3-(乙酰氨基)苯甲酸甲酯合成路线 （共 8 条）
反应条件
4-(N,N-dimethlyamino)pyridine; N-ethyl-N,N-diisopropylamine in dichloromethane
T=20°C;
参考文献
Laird, Ellen; Topalov, George; Lyssikatos, Joseph P.; Welch, Mike; Grina, Jonas; Hansen, Josh; Newhouse, Brad
Patent: US2006/281751 A1, 2006 ;
Location in patent: Page/Page column 25-26 ;
US 20060281751 A1
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
参考文献
Yang, Xiaowu; Yuan, Lihua; Yamato, Kazuhiro; Brown, Amy L.; Feng, Wen; Furukawa, Mako; Zeng, Xiao Cheng; Gong, Bing
Journal of the American Chemical Society, 2004 , vol. 126, # 10 p. 3148 - 3162
参考文献
Yang, Haishen; Zhou, Lei; Wang, Pengfei
Photochemical and Photobiological Sciences, 2012 , vol. 11, # 3 p. 514 - 517
反应条件
1: 56 percent / 12 h / Ambient temperature
2: 80 percent / MCPBA / CH2Cl2 / 1 h / 0 °C
3: 1.) hydroquinone, 2.) NaOH / 1.) PhMe, 165 deg C, 6 h, 2.) MeOH, r.t., 2 h
View Scheme
参考文献
Chou, Shang-Shing P.; Chow, Tahsin J.; Hsu, Chien-Hung; Yang, Chengda; Long, Shu-Hua; Lin, Chih-Da
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 11 p. 1691 - 1697
反应条件
1: 80 percent / MCPBA / CH2Cl2 / 1 h / 0 °C
2: 1.) hydroquinone, 2.) NaOH / 1.) PhMe, 165 deg C, 6 h, 2.) MeOH, r.t., 2 h
View Scheme
参考文献
Chou, Shang-Shing P.; Chow, Tahsin J.; Hsu, Chien-Hung; Yang, Chengda; Long, Shu-Hua; Lin, Chih-Da
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 11 p. 1691 - 1697
反应条件
1: sulfuric acid / |Reflux
2: triethylamine / dichloromethane / 20 °C
View Scheme
参考文献
Lu, Wenya; Tian, Chong; Thogaripally, Punith; Hu, Jun; Wang, Pengfei
Chemical Communications, 2013 , vol. 49, # 83 p. 9636 - 9638
参考文献
Budesinsky, Milos; Exner, Otto
Magnetic Resonance in Chemistry, 1989 , vol. 27, # 6 p. 585 - 591
反应条件
sodium hydroxide; hydroquinone
1.) PhMe, 165 deg C, 6 h, 2.) MeOH, r.t., 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Chou, Shang-Shing P.; Chow, Tahsin J.; Hsu, Chien-Hung; Yang, Chengda; Long, Shu-Hua; Lin, Chih-Da
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 11 p. 1691 - 1697
