Alpha-甲基-(3-氧代环己基)丙二酸二乙酯合成路线 (共 3 条)
反应条件
indium; chloro-trimethyl-silane in tetrahydrofuran
T=20°C; Michael addition reaction; 0.5 h;
参考文献
Lee, Phil Ho; Seomoon, Dong; Lee, Kooyeon; Heo, Yunkiu
Journal of Organic Chemistry, 2003 , vol. 68, # 6 p. 2510 - 2513
反应条件
sodium; acetic acid in diethyl ether; ethanol
参考文献
Hoffmann-La Roche Inc.
Patent: US4264500 A1, 1981 ;
反应条件
palladium on activated charcoal; ethyl acetate
Hydrogenation;
参考文献
Abe et al.
Yakugaku Zasshi, 1953 , vol. 73, p. 36
Chem.Abstr., 1953 , p. 10489
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Abe et al.
Proceedings of the Japan Academy, 1952 , vol. 28, p. 425
Journal of the American Chemical Society, 1956 , vol. 78, p. 1416,1420