N-羟基邻苯二甲酰亚胺合成路线 （共 297 条）
反应条件
dicyclohexyl-carbodiimide in ethyl acetate 3 h; Ambient temperature;
参考文献
Saljoughian, Manouchehr; Morimoto, Hiromi; Williams, Philip G.; Than, Chit; Seligman, Stephen J.
Journal of Organic Chemistry, 1996 , vol. 61, # 26 p. 9625 - 9628
反应条件
1: 2-hydroxy-1,3-isoindolinedione With caesium carbonate in N,N-dimethyl-formamide Solid phase reaction; 2: acetyl-bromide With zinc dibromide in dichloromethane Solid phase reaction; 24 h;
参考文献
Li, Wen-Ren; Yo, Ying-Chih
Tetrahedron Letters, 1999 , vol. 40, # 51 p. 9085 - 9089
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane 3 h;
参考文献
Malmstroem, Eva; Miller, Robert D.; Hawker, Craig J.
Tetrahedron, 1997 , vol. 53, # 45 p. 15225 - 15236
反应条件
Mn(OAc)3•2H2O in acetic acid T=60°C; 0.75 h;
参考文献
Terent'Ev, Alexander O.; Krylov, Igor B.; Timofeev, Vladimir P.; Starikova, Zoya A.; Merkulova, Valentina M.; Ilovaisky, Alexey I.; Nikishin, Gennady I.
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 11-12 p. 2375 - 2390
参考文献
Saha, Basudeb; Koshino, Nobuyoshi; Espenson, James H.
Journal of Physical Chemistry A, 2004 , vol. 108, # 3 p. 425 - 431
反应条件
1: 2-hydroxy-1,3-isoindolinedione With sodium hydride in N,N-dimethyl-formamide Metallation; 2: benzyl bromide With sodium iodide in N,N-dimethyl-formamide T=70°C; Alkylation; 22 h;
参考文献
High; Prior; Bell; Rangachari
Journal of Pharmacology and Experimental Therapeutics, 1999 , vol. 288, # 2 p. 490 - 501
反应条件
[bis(acetoxy)iodo]benzene; copper(l) chloride in acetonitrile T=70°C; 12 h; Inert atmosphere;
参考文献
Ji, Min Lee; Eun, Ju Park; Seung, Hwan Cho; Chang, Sukbok
Journal of the American Chemical Society, 2008 , vol. 130, # 25 p. 7824 - 7825
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=25°C; 18 h;
参考文献
Kim, Sunggak; Lee, Tai Au; Song, Yukwan
Synlett, 1998 , # 5 p. 471 - 472
反应条件
sodium carbonate in water; N,N-dimethyl-formamide; acetonitrile 4 h;
参考文献
Uhlmann, Peter; Felding, Jakob; Vedso, Per; Begtrup, Mikael
Journal of Organic Chemistry, 1997 , vol. 62, # 26 p. 9177 - 9181
反应条件
triethylamine in N,N-dimethyl-formamide T=70°C; Condensation;
参考文献
Bartovic; Decroix; Netchitailo
Journal of Heterocyclic Chemistry, 2000 , vol. 37, # 4 p. 827 - 830
