5-氯-2，3-二苯基吲哚合成路线 （共 17 条）
反应条件
2 mol Pd/C; sodium carbonate in N,N-dimethyl-formamide
T=140°C; Larock heteroannulation; 144 h; Inert atmosphere; regioselective reaction;
参考文献
Batail, Nelly; Dufaud, Veronique; Djakovitch, Laurent
Tetrahedron Letters, 2011 , vol. 52, # 16 p. 1916 - 1918
反应条件
samarium; titanium tetrachloride in tetrahydrofuran
1 h; Heating;
参考文献
Fan, Xuesen; Zhang, Xinying
Journal of Chemical Research - Part S, 2003 , # 11 p. 696 - 697
反应条件
1: With Cp*Rh(H2O)3(OTf)2; oxygen; acetic anhydride in 1,1-dimethylpropan-1-ol
T=40°C; P=760.051 Torr; 24 h; Inert atmosphereSchlenk technique;
2: With sodium hydroxide in methanol; 1,1-dimethylpropan-1-ol
T=20°C; 1 h;
参考文献
Zhang, Guoying; Yu, Hui; Qin, Guiping; Huang, Hanmin
Chemical Communications, 2014 , vol. 50, # 33 p. 4331 - 4334
反应条件
[(η5-C5Me5)2Rh2(μ-Cl)2Cl2]; sodium acetate; acetic acid; pentan-3-one in ethanol
T=110°C; 20 h; Sealed tubeInert atmosphere; regioselective reaction;
参考文献
Muralirajan, Krishnamoorthy; Cheng, Chien-Hong
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 7 p. 1571 - 1576
反应条件
samarium diiodide in tetrahydrofuran
T=-20°C; 0.0833333 h;
参考文献
Fan, Xuesen; Zhang, Yongmin
Tetrahedron, 2003 , vol. 59, # 11 p. 1917 - 1923
反应条件
silver hexafluoroantimonate; [{(η5-C5Me5)RhCl}2(μ-Cl)2]; copper (II) acetate monohydrate in methanol
T=90°C; Schlenk techniqueInert atmosphere; regioselective reaction;
参考文献
Wang, Chengming; Sun, Huan; Fang, Yan; Huang, Yong
Angewandte Chemie - International Edition, 2013 , vol. 52, # 22 p. 5795 - 5798
Angew. Chem., 2013 , p. 5999
反应条件
[{(η5-C5Me5)RhCl}2(μ-Cl)2]; caesium acetate; acetic acid in 1,2-dichloro-ethane
T=70°C; 16 h; Inert atmosphere;
参考文献
Zhao, Dongbing; Shi, Zhuangzhi; Glorius, Frank
Angewandte Chemie - International Edition, 2013 , vol. 52, # 47 p. 12426 - 12429
Angew. Chem., 2013 , vol. 125, # 47 p. 12652 - 12656,4
反应条件
phosphorus trichoride in dichloromethane
2 h; Ambient temperature;
参考文献
Baccolini, Graziano; Marotta, Emanuela
Tetrahedron, 1985 , vol. 41, # 20 p. 4615 - 4620
反应条件
1: With Cp*Rh(H2O)3(OTf)2; oxygen; acetic anhydride in 1,1-dimethylpropan-1-ol
T=100°C; P=760.051 Torr; 2 h; Inert atmosphereSchlenk technique;
2: With sodium hydroxide in methanol; 1,1-dimethylpropan-1-ol
T=20°C; 1 h;
参考文献
Zhang, Guoying; Yu, Hui; Qin, Guiping; Huang, Hanmin
Chemical Communications, 2014 , vol. 50, # 33 p. 4331 - 4334
反应条件
1.1: hydrogenchloride; sodium nitrite / acetonitrile; water / 0.5 h / -5 - 0 °C
1.2: 0 °C
2.1: [(η5-C5Me5)2Rh2(μ-Cl)2Cl2]; copper (II) acetate monohydrate; silver hexafluoroantimonate / methanol / 90 °C / |Schlenk technique; |Inert atmosphere
View Scheme
参考文献
Wang, Chengming; Sun, Huan; Fang, Yan; Huang, Yong
Angewandte Chemie - International Edition, 2013 , vol. 52, # 22 p. 5795 - 5798
Angew. Chem., 2013 , p. 5999
