2,6-二羟基-4-甲基苯甲醛合成路线 （共 32 条）
反应条件
1.1: 93 percent / sodium hydride / dimethylformamide; various solvent(s) / 18 h / 18 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 0 - 18 °C
2.2: 73 percent / tetrahydrofuran; hexane / 18 °C
3.1: 91 percent / acetyl chloride / methanol / 20 h / 18 °C
View Scheme
参考文献
Banwell, Martin G.; Chand, Satish
Organic Preparations and Procedures International, 2005 , vol. 37, # 3 p. 275 - 279
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0 - 18 °C
1.2: 73 percent / tetrahydrofuran; hexane / 18 °C
2.1: 91 percent / acetyl chloride / methanol / 20 h / 18 °C
View Scheme
参考文献
Banwell, Martin G.; Chand, Satish
Organic Preparations and Procedures International, 2005 , vol. 37, # 3 p. 275 - 279
反应条件
1: 86 percent / BCl3 / CH2Cl2 / 3.5 h / Ambient temperature
2: 96 percent / BBr3 / CH2Cl2 / 27 h / Ambient temperature
3: 81 percent / Cu2O, 2,2'-bipyridyle / bis-(2-methoxy-ethyl) ether / 9 h / Heating
View Scheme
参考文献
Pulgarin, Cesar; Tabacchi, Raffaele
Helvetica Chimica Acta, 1989 , vol. 72, p. 1061 - 1065
反应条件
1: aluminium chloride; diethyl ether / Einleiten von Chlorwasserstoff; Erwaermen des Reaktionsprodukts mit Wasser
2: sulfuric acid
3: 100 - 120 °C
View Scheme
参考文献
Pfau
Helvetica Chimica Acta, 1933 , vol. 16, p. 282,286
参考文献
Asahina; Asano
Yakugaku Zasshi, 1933 , vol. 53, p. 1154,1171
Chemische Berichte, 1933 , vol. 66, p. 689,698, 893, 895
参考文献
Suominen
Suomen Kemistilehti B, 1939 , vol. 12, p. 26
参考文献
Asahina; Asano; Tanase
Yakugaku Zasshi, 1933 , vol. 53, p. 1176,1180
Full Text Show Details
Asahina; Tanase
Chemische Berichte, 1933 , vol. 66, p. 700,703
Yakugaku Zasshi, 1933 , vol. 53, p. 1176
参考文献
Adams; Mathieu
Journal of the American Chemical Society, 1948 , vol. 70, p. 2120
参考文献
Asahina et al.
Chemische Berichte, 1933 , vol. 66, p. 943,1084
反应条件
T=230 - 250°C; 0.75 h; pyrolysis; Product distribution;
参考文献
Huneck, Siegfried; Schmidt, Juergen; Tabacchi, Raffaele
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1989 , vol. 44, # 10 p. 1283 - 1289
