1-溴-2-(甲氧基甲基)苯合成路线 （共 24 条）
反应条件
1: o-bromo-benzyl alcohol With sodium hydride in tetrahydrofuran; mineral oil T=0°C; 1 h; Inert atmosphere; 2: methyl iodide in tetrahydrofuran; mineral oil T=0 - 20°C; 1.75 h; Inert atmosphere;
参考文献
Adamczyk-Wozniak, Agnieszka; Brzozka, Zbigniew; Dabrowski, Marek; Madura, Izabela D.; Scheidsbach, Roy; Tomecka, Ewelina; Zukowski, Kamil; Sporzynski, Andrzej
Journal of Molecular Structure, 2013 , vol. 1035, p. 190 - 197
反应条件
sodium methylate in methanol; ethyl acetate
参考文献
Supniewski; Adams
Journal of the American Chemical Society, 1926 , vol. 48, p. 516
参考文献
Dutta, Dipak Kumar; Deb, Biswajit; Hua, Guoxiong; Woollins, J. Derek
Journal of Molecular Catalysis A: Chemical, 2012 , vol. 353-354, p. 7 - 12
反应条件
sodium methylate; sodium in methanol
参考文献
Laboratoires UPSA
Patent: US5389632 A1, 1995 ;
US 5389632 A
反应条件
sodium 3 h; Heating;
参考文献
Christenson, Beritte; Hallnemo, Gerd; Ullenius, Christina
Tetrahedron, 1991 , vol. 47, # 26 p. 4739 - 4752
反应条件
1: NBS, benzoyl peroxide / CCl4 2: CH3ONa View Scheme
参考文献
Supniewski; Adams
Journal of the American Chemical Society, 1926 , vol. 48, p. 516
参考文献
Yamato; Sakaue; Tanaka; Tsuzuki
New Journal of Chemistry, 2001 , vol. 25, # 3 p. 434 - 439
参考文献
Woolford,R.G.; Lin,W.S.
Canadian Journal of Chemistry, 1966 , vol. 44, p. 2783 - 2791
反应条件
n-butyllithium 1.) Et2O, -78 deg C, 1.5 h 2.) -78 deg C -> 20 deg C; Yield given. Multistep reaction;
参考文献
Nakamura, Yosuke; O-kawa, Kyoji; Minami, Satoshi; Ogawa, Toshio; Tobita, Seiji; Nishimura, Jun
Journal of Organic Chemistry, 2002 , vol. 67, # 4 p. 1247 - 1252
反应条件
1: pyridine 2: aq.-ethanolic NaOH 3: LiAlH4; diethyl ether 4: SOBr2; pyridine; CHCl3 6: aqueous sulfuric acid View Scheme
参考文献
Journal of the Chemical Society, , p. 2819,2824
