1: With copper(l) iodide; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran
T=20°C; 2.5 h;
2: With water in tetrahydrofuran
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/19184 A1, 2005 ;
Location in patent: Page/Page column 50 ;
WO 2005/019184 A1
ammonia; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; water
T=20°C; P=760 Torr; 24 h;
参考文献
Mohamed Ahmed, Mohamed S.; Sekiguchi, Akitoshi; Masui, Kentaro; Mori, Atsunori
Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 1 p. 160 - 168
