1,2,3,4-四氢-1-萘酚合成路线 （共 211 条）
反应条件
C6F5NH3(1+)*OTf(1-)
T=90°C; Ritter reaction; 2 h; Neat (no solvent); chemoselective reaction;
参考文献
Khaksar, Samad; Fattahi, Eskandar; Fattahi, Esmail
Tetrahedron Letters, 2011 , vol. 52, # 45 p. 5943 - 5946
反应条件
1: C40H36Cl2FeN2P2Ru; potassium tert-butylate / tert-butyl alcohol / 3 h / 130 °C / Inert atmosphere
2: trans-[OsCl2(1,1'-bis(diphenylphosphino)ferrocene)(2-aminomethylpyridine)]; potassium tert-butylate / toluene; tert-butyl alcohol / 0.5 h / 120 °C / Inert atmosphere
View Scheme
参考文献
Putignano, Elisabetta; Bossi, Gianluca; Rigo, Pierluigi; Baratta, Walter
Organometallics, 2012 , vol. 31, # 3 p. 1133 - 1142
反应条件
thionyl chloride in toluene
T=55°C; 1 h;
参考文献
Ahmad, Youssef El; Laurent, Elisabeth; Maillet, Philippe; Talab, Akram; Teste, Jean Francois; Dokhan, Raymond; Tran, Gilles; Ollivier, Roland
Journal of Medicinal Chemistry, 1997 , vol. 40, # 6 p. 952 - 960
反应条件
tetrachlorosilane in chloroform
T=20°C; 5 h;
参考文献
Firouzabadi, Habib; Iranpoor, Naser; Karimi, Babak; Hazarkhani, Hassan
Synthetic Communications, 2003 , vol. 33, # 21 p. 3671 - 3677
反应条件
chloro-trimethyl-silane; dimethyl sulfoxide in acetonitrile
Heating;
参考文献
Bellesia, Franco; Ghelfi, Franco; Pagnoni, Ugo Maria; Pinetti, Adriano
Gazzetta Chimica Italiana, 1992 , vol. 122, # 10 p. 437 - 439
反应条件
triethylamine in diethyl ether
参考文献
Fournier; Berthelot; Pavard; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 1 p. 48 - 58
反应条件
1: AlCl3 / hexane
2: NaOH
View Scheme
参考文献
Bencze,W.L. et al.
Tetrahedron, 1970 , vol. 26, p. 5407 - 5414
反应条件
1: 34 percent / n-BuLi; TMEDA / pentane; hexane / -78 - 20 °C
2: 41 percent / CrO3; AcOH / H2O / 12 h / 20 °C
3: 62 percent / diethyl ether / 140 h / 40 °C
4: 40 percent / K3PO4; Pd(dba)2; bis[2-(diphenylphosphino)phenyl] ether / toluene / 24 h / 110 °C
View Scheme
参考文献
Lebedev, Artyom Y.; Khartulyari, Anton S.; Voskoboynikov, Alexander Z.
Journal of Organic Chemistry, 2005 , vol. 70, # 2 p. 596 - 602
反应条件
in 1,1-dimethylpropan-1-ol
Heating;
参考文献
Felix,D. et al.
Helvetica Chimica Acta, 1969 , vol. 52, p. 1030 - 1042
反应条件
1: toluene-4-sulfonic acid / toluene / 4 h / 80 - 110 °C / |Inert atmosphere
2: 1,3-dibromo-5,5-dimethyl-hydantoin / toluene; acetone; water / 5 h / 0 - 25 °C / |Inert atmosphere; |Large scale
View Scheme
参考文献
Gala, Dinesh; Dahanukar, Vilas H.; Eckert, Jeffery M.; Lucas, Brian S.; Schumacher, Doris P.; Zavialov, Ilia A.; Buholzer, Patrik; Kubisch, Peter; Mergelsberg, Ingrid; Scherer, Dominik
Organic Process Research and Development, 2004 , vol. 8, # 5 p. 754 - 768
