1: (+/-)-1-cyano-1,2,3,4-tetrahydronaphthalen-1-yl acetate With immobilized Candida antarctica lipase A; water in 2-ethoxy-2-methylpropane 168 h; Enzymatic reaction; 2: chloro-trimethyl-silane With pyridine in dichloromethane T=20°C; 6 h; optical yield given as percent eeenantioselective reaction;
1: (+/-)-1-cyano-1,2,3,4-tetrahydronaphthalen-1-yl acetoxyacetate With immobilized Candida antarctica lipase A; water in 1,4-dioxane T=40°C; 144 h; Enzymatic reaction; 2: chloro-trimethyl-silane With pyridine in dichloromethane T=20°C; 6 h; optical yield given as percent eeenantioselective reaction;
immobilized Candida antarctica lipase A; water in tetrahydrofuran T=40°C; 168 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
1: With boron trifluoride diethyl etherate; [Pd(CH3CN)4](BF4)2 in various solvent(s) Friedel-Crafts cyclization; 6 h; Heating; 2: With phosphate buffer in various solvent(s) pH=7; Further stages.;
