2-硝基对苯二甲酸二甲酯合成路线 （共 23 条）
反应条件
hydrogen; palladium on activated charcoal in methanol; N,N-dimethyl-formamide Ambient temperature;
参考文献
Weinges, Klaus; Reinel, Ute; Maurer, Wolfgang; Gaessler, Norbert
Liebigs Annalen der Chemie, 1987 , p. 833 - 838
反应条件
ethanol; hydrogen sulfide; ammonia
参考文献
Cohen; Mc Candlish
Journal of the Chemical Society, 1905 , vol. 87, p. 1265
反应条件
in N,N-dimethyl-formamide
T=-30°C;
参考文献
Breslow, Ronald; Guo, Tao
Tetrahedron Letters, 1987 , vol. 28, # 28 p. 3187 - 3188
参考文献
Ackrell,J. et al.
Journal of Medicinal Chemistry, 1978 , vol. 21, p. 1035 - 1040
反应条件
sodium hydroxide in methanol; ethanol; water; dimethyl sulfoxide
参考文献
Burroughs Welcome Co.
Patent: US4902701 A1, 1990 ;
反应条件
diisobutylaluminium hydride in toluene
T=-78°C;
参考文献
Hwang, Gil Tae; Son, Hyung Su; Ku, Ja Kang; Kim, Byeang Hyean
Journal of the American Chemical Society, 2003 , vol. 125, # 37 p. 11241 - 11248
反应条件
1: 72 percent / 1N aq. NaOH / dioxane / 0.5 h / Ambient temperature
2: (COCl)2, DMF / toluene
View Scheme
参考文献
Wang, Min; Davis, Toni; Gao, Mingzhang; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1742 - 1747
反应条件
potassium hydroxide in methanol; water; N,N-dimethyl-formamide; paraffin
参考文献
Ciba-Geigy Corporation
Patent: US4506083 A1, 1985 ;
反应条件
1: dimethylformamide / -30 °C
2: 1.) KOH, 2.) H+
View Scheme
参考文献
Breslow, Ronald; Guo, Tao
Tetrahedron Letters, 1987 , vol. 28, # 28 p. 3187 - 3188
反应条件
1: para-thiocresol With sodium hydroxide in N,N-dimethyl-formamide
T=20°C; 0.5 h;
2: dimethyl 2-nitro-1,4-benzenedicarboxylate in N,N-dimethyl-formamide
T=75°C; 1.5 h;
参考文献
LAMBERTI SPA; CASIRAGHI, Angelo; MENEGUZZO, Enzo; NORCINI, Gabriele; BELLOTTI, Elena; FLORIDI, Giovanni; LI BASSI, Giuseppe
Patent: WO2012/62692 A1, 2012 ;
Location in patent: Page/Page column 10 ;
