sodium hydroxide in dichloromethane 0.25 h;

1: cyclohexanecarbaldehyde With 1-hydroxy-pyrrolidine-2,5-dione; oxygen; [Co(O2CCH3)2]*4H2O; sodium hydrogencarbonate in acetonitrile T=20°C; P=760.051 Torr; 1 h; Molecular sieve; 2: [14C]-2-Phenylethylamine hydrochloride in acetonitrile T=20°C; Molecular sieve;

4-(N,N-dimethlyamino)pyridine in chloroform T=25°C; 1 h;

1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; tetrabutylammomium bromide / acetonitrile / 20 °C / |Inert atmosphere 2: aluminum oxide / toluene; acetonitrile / 1 h / 130 °C / |Microwave irradiation; |Inert atmosphere View Scheme

T=180 - 190°C;

xylene; trichlorophosphate

1: P2O5; POCl3 / xylene / 2.5 h / Heating 2: NaBH4 / ethanol / 60 h / 20 °C View Scheme