反应条件
1: 95 percent / conc. H2SO4, acetone / Ambient temperature 2: pyridine / CH2Cl2 / 0 °C 3: 4 M H2SO4, 85percent AcOH / tetrahydrofuran / 60 °C 4: I2, Ph3P, imidazole / CH2Cl2 / Ambient temperature 5: NIS / 1,2-dichloro-ethane / Ambient temperature 6: 51 percent / Zn, AcOH / ethanol; ethyl acetate / 70 °C 7: 50 percent / n-BuNH2 / tetrahydrofuran View Scheme
参考文献
Chen, Shu-Hui; Lin, Stanley; King, Ivan; Spinka, Tracy; Dutschman, Ginger E.; Gullen, Elizabeth A.; Cheng, Yung-Chi; Doyle, Terrence W.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 22 p. 3245 - 3250