3-乙氧基-2-环己烯-1-酮合成路线 （共 132 条）
反应条件
1: 3-ethoxy-2-cyclohexen-1-one With 1,1,1,2,2,2-hexabutyl-distannane in tetrahydrofuran 2: With n-butyllithium in tetrahydrofuran 3: methyl iodide With cesium fluoride; tris-(o-tolyl)phosphine; copper(I) bromide; tris(dibenzylideneacetone)dipalladium (0) in tetrahydrofuran Stille coupling;
参考文献
Hosoya, Takamitsu; Sumi, Kengo; Doi, Hisashi; Wakao, Masahiro; Suzuki, Masaaki
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 3 p. 410 - 415
反应条件
diethyl ether; methyllithium
参考文献
Meinwald; Grossman
Journal of the American Chemical Society, 1956 , vol. 78, p. 992
反应条件
copper(l) chloride in tetrahydrofuran T=0°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Cahiez, Gerard; Alami, Mouad
Tetrahedron Letters, 1989 , vol. 30, # 27 p. 3541 - 3544
反应条件
in diethyl ether T=-20 - 20°C;
参考文献
Weidmann, Beat; Maycock, Christopher D.; Seebach, Dieter
Helvetica Chimica Acta, 1981 , vol. 64, # 5 p. 1552 - 1557
反应条件
Behandeln des Reaktionsgemisches mit wss.H2SO4 und anschliessenden Einleiten von Wasserdampf;
参考文献
Woods et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 2028
反应条件
1: 1.) LDA, HMPA / 1.) THF, hexane, -45 deg C, 0.5 h; 2.) THF, hexane, -45 deg C, 1 h 2: LAH / tetrahydrofuran / 0.5 h / Ambient temperature 3: 1N HCl / tetrahydrofuran / 0.08 h / Ambient temperature 4: H2 / 10percent Pd-C / ethyl acetate / 2 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 50, # 12 p. 3673 - 3686
反应条件
1: diethyl ether / -40 °C / Destillation des nach der Hydrolyse erhaltenen Reaktionsprodukts mit Wasser-Dampf View Scheme
参考文献
Woods et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 2028
反应条件
2: Li, liq. NH3 View Scheme
参考文献
Conia,J.-M.; Breslin,P.
Bulletin de la Societe Chimique de France, 1969 , p. 483 - 488
反应条件
1.1: diethyl ether / 3 h / Heating 1.2: 75 percent / aq. HCl / diethyl ether / 2.5 h / 20 °C 2.1: CuI / diethyl ether; hexane / 0.33 h 2.2: 51 percent / hexane; diethyl ether / 2.5 h / 0 °C View Scheme
参考文献
Zimmerman, Howard E.; Nesterov, Evgueni E.
Journal of the American Chemical Society, 2003 , vol. 125, # 18 p. 5422 - 5430
反应条件
dichloro bis(acetonitrile) palladium(II) T=20°C; P=15 Torr; 6 h; Product distribution / selectivity;
参考文献
Mitsubishi Chemical Corporation
Patent: JP2005/170912 A, 2005 ;
Location in patent: Page/Page column 9 ;
