2-羟基-2-(噻吩-2-基)乙酸合成路线 （共 12 条）
反应条件
sodium hydroxide; nickel-aluminium
参考文献
Gronowitz
Arkiv foer Kemi, 1957 , vol. 11, p. 519,524
参考文献
Sagami Chemical Research Center
Patent: US4266067 A1, 1981 ;
反应条件
in acetonitrile T=443.4°C; Pyrolysis; Kinetics; Further Variations:Temperatures;
参考文献
Al-Juwaiser, Ibtehal A.; Al-Awadi, Nouria A.; El-Dusouqui, Osman M.E.
Canadian Journal of Chemistry, 2002 , vol. 80, # 5 p. 499 - 503
反应条件
sodium hydroxide in water
参考文献
Sagami Chemical Research Center
Patent: US4266067 A1, 1981 ;
反应条件
1: With water; potassium hydroxide in methanol
T=0 - 25°C;
2: With hydrogenchloride in water
pH=<= 1;
参考文献
Ranbaxy Laboratories Limited
Patent: EP2130830 A1, 2009 ;
Location in patent: Page/Page column 10 ;
EP 2130830 A1
反应条件
potassium hydroxide; lithium chloride in 1,4-dioxane; water
参考文献
Sagami Chemical Research Center
Patent: US4221915 A1, 1980 ;
反应条件
hydrogenchloride; sodium hydroxide; sodium chloride in water
参考文献
Sagami Chemical Research Center
Patent: US4266067 A1, 1981 ;
反应条件
cesium fluoride in N,N-dimethyl-formamide
T=60°C; P=760.051 Torr; 24 h;
参考文献
Mita, Tsuyoshi; Higuchi, Yuki; Sato, Yoshihiro
Organic Letters, 2014 , vol. 16, # 1 p. 14 - 17
反应条件
selenium(IV) oxide in 1,4-dioxane; water
T=90°C; Cannizzaro Reaction; 24 h;
参考文献
Shen, Ming-Gui; Shang, Shi-Bin; Song, Zhan-Qian; Wang, Dan; Rao, Xiao-Ping; Gao, Hong; Liu, He
Journal of Chemical Research, 2013 , vol. 37, # 1 p. 51 - 52
反应条件
calcium hydroxide powder; water; dichlorobis(trimethylphosphine)palladium in isopropyl alcohol
T=100°C; 12 h; P(CO) = 150 atm at room temperature;
参考文献
Kobayashi, Toshi-aki; Sakakura, Toshiyasu; Tanaka, Masato
Tetrahedron Letters, 1987 , vol. 28, # 24 p. 2721 - 2722
