3-((哌啶-1-基)甲基)-1H-吲哚合成路线 （共 19 条）
反应条件
1: 85 percent / acetic anhydride / 1,2-dimethoxy-ethane / Ambient temperature
2: 85 percent / 1 h / Heating
View Scheme
参考文献
Jacobs, Robert T.; Wright, Allen D.; Smith, Francis X.
Journal of Organic Chemistry, 1982 , vol. 47, # 19 p. 3769 - 3772
参考文献
Jacobs, Robert T.; Wright, Allen D.; Smith, Francis X.
Journal of Organic Chemistry, 1982 , vol. 47, # 19 p. 3769 - 3772
反应条件
1: benzene / 1.5 h / Heating; removing the liberated water
2: 77 percent / sodium borohydride / ethanol / 3 h / Ambient temperature
View Scheme
参考文献
Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721
反应条件
potassium tert-butylate in tetrahydrofuran
2 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Love, Brian E.; Nguyen, Binh T.
Synlett, 1998 , # 10 p. 1123 - 1125
参考文献
Howe et al.
Journal of the American Chemical Society, 1945 , vol. 67, p. 38
反应条件
1: potassium carbonate; sodium sulfate / 20 °C / |Inert atmosphere
2: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 0.5 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Sakai, Norio; Okano, Hidetoshi; Shimamura, Kazuyori; Konakahara, Takeo
Chemistry Letters, 2014 , vol. 43, # 4 p. 501 - 503
反应条件
1: potassium carbonate; sodium sulfate / 20 °C / |Inert atmosphere
2: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 0.5 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Sakai, Norio; Okano, Hidetoshi; Shimamura, Kazuyori; Konakahara, Takeo
Chemistry Letters, 2014 , vol. 43, # 4 p. 501 - 503
参考文献
Hellmann; Teichmann
Chemische Berichte, 1958 , vol. 91, p. 2432,2436
参考文献
Snyder et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 4672,4674
