3-氨基-4-羟基苯甲酸甲酯合成路线 （共 42 条）
反应条件
2: bei der Destillation unter vermindertem Druck View Scheme
参考文献
v. Meyer
Journal fuer Praktische Chemie (Leipzig), 1915 , vol. <2> 92, p. 265
参考文献
Sarangapani; Sridhar; Arjun; Adharvana Chari
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 4 p. 1187 - 1190
反应条件
1.1: acetic acid / 3.5 h / 60 °C / |Large scale 2.1: potassium carbonate / N,N-dimethyl-formamide / 7 h / 60 °C / |Large scale 3.1: nitric acid / nitromethane / 8 h / 20 - 35 °C / |Large scale 4.1: hydrogen / methanol / 12 h / 20 °C / 760.05 Torr / |Large scale 5.1: acetic acid / 5 h / 20 °C / |Large scale 6.1: sodium t-butanolate / tert-butyl alcohol / 3 h / |Reflux; |Large scale 6.2: 1 h / 40 - 50 °C / pH Ca. 4 / |Large scale 7.1: trichlorophosphate; 4-(N,N-dimethlyamino)pyridine / ethyl acetate / 3 h / |Reflux; |Large scale View Scheme
参考文献
Mao, Yongjun; Liu, Zheng; Yang, Xiaojun; Xia, Xiangfei; Zhang, Rongxia; Li, Jianfeng; Jiang, Xiangrui; Xie, Kai; Zheng, Jin; Zhang, Hui; Suo, Jin; Shen, Jingshan
Organic Process Research and Development, 2012 , vol. 16, # 12 p. 1970 - 1973
反应条件
potassium carbonate in N,N-dimethyl-formamide T=70°C;
参考文献
Ackermann, Jean; Bleicher, Konrad; Ceccarelli, Simona M.; Chomienne, Odile; Mattei, Patrizio; Sander, Ulrike Obst
Patent: US2007/191603 A1, 2007 ;
Location in patent: Page/Page column 25 ;
反应条件
1: pyridine 2: 180 °C View Scheme
参考文献
Einhorn; Ruppert
Justus Liebigs Annalen der Chemie, 1902 , vol. 325, p. 320
反应条件
sodium hydroxide; toluene
参考文献
Einhorn; Ruppert
Justus Liebigs Annalen der Chemie, 1902 , vol. 325, p. 320
参考文献
Mohamed, Nadia A.; Sammour, Mohammad H.; Elshafai, Ali M.
Molecules, 2012 , vol. 17, # 12 p. 13969 - 13988
反应条件
1: benzene 2: potassium carbonate; diluted alcohol 3: diluted natrium carbonate View Scheme
参考文献
Einhorn; Oppenheimer
Justus Liebigs Annalen der Chemie, 1900 , vol. 311, p. 168
参考文献
v. Meyer
Journal fuer Praktische Chemie (Leipzig), 1915 , vol. <2> 92, p. 265
参考文献
Sarangapani; Sridhar; Arjun; Adharvana Chari
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 4 p. 1187 - 1190
