反应条件
1: phenylacetylene With n-butyllithium in tetrahydrofuran; hexane
T=0°C; 1.5 h; Inert atmosphere;
2: 1-iodo-4-[(tetrahydropyran-2-yl)oxy]butane With N,N,N',N',N'',N''-hexamethylphosphoric triamide in tetrahydrofuran; hexane
T=0 - 20°C; 12.5 h; Inert atmosphere;
3: With toluene-4-sulfonic acid in methanol; water
T=20°C; 2 h; Inert atmosphere;
参考文献
Miura, Katsukiyo; Yamamoto, Kiyomi; Yamanobe, Aya; Ito, Keisuke; Kinoshita, Hidenori; Ichikawa, Junji; Hosomi, Akira
Chemistry Letters, 2010 , vol. 39, # 7 p. 766 - 767
