3-羟基-4-甲氧基肉桂酸合成路线 （共 20 条）
参考文献
Hoffmann
Chemische Berichte, 1876 , vol. 9, p. 686
反应条件
methanol; potassium hydroxide
参考文献
Tiemann; Will
Chemische Berichte, 1881 , vol. 14, p. 967
参考文献
Tanaka, Reiko; Inosiri, Atsuyo; Yoneda, Michiko; Ishida, Toshimasa; Numada, Atsushi; et al.
Phytochemistry (Elsevier), 1990 , vol. 29, # 10 p. 3263 - 3265
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; 2 h;
参考文献
Braune, Annett; Engst, Wolfram; Blaut, Michael
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 5 p. 1782 - 1790
参考文献
Tiemann; Nagai
Chemische Berichte, 1878 , vol. 11, p. 656
反应条件
1: 97 percent / p-TsOH / 24 h / Heating 2: 100 percent / H2 / 10percent Pd/C / aq. ethanol / Ambient temperature View Scheme
参考文献
Robinson; Sugasawa
Journal of the Chemical Society, 1931 , p. 3163,3168
Journal of the Chemical Society, 1933 , p. 280
反应条件
thionyl chloride 4 h; Reflux;
参考文献
Sun, Jie; Ding, Wei-Xian; Hong, Xiao-Ping; Zhang, Ke-Yun; Zou, Yong
Chemistry of Natural Compounds, 2012 , vol. 48, # 1 p. 16 - 22
反应条件
1: 100 percent / H2 / Pd/C / ethyl acetate; methanol / 5 h / 2172.02 Torr
2: K2CO3 / acetone; acetonitrile / 25 h / Heating
3: 1.02 g / KOH / methanol; H2O / 10 h / 70 °C
4: oxalyl chloride / CH2Cl2 / 20 h / 20 °C
5: tetrahydrofuran; hexane; acetonitrile / 4 h
View Scheme
参考文献
Li, Dajie; Zhao, Baoping; Sim, Sai-Peng; Li, Tsai-Kun; Liu, Angela; Liu, Leroy F.; LaVoie, Edmond J.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 17 p. 3795 - 3805
反应条件
1: 28 percent / bromine / acetic acid
2: 6 percent / Pd(PPh3)4; aq. Na2CO3 / 1,2-dimethoxy-ethane / Heating
View Scheme
参考文献
Gaukroger, Keira; Hadfield, John A.; Hepworth, Lucy A.; Lawrence, Nicholas J.; McGown, Alan T.
Journal of Organic Chemistry, 2001 , vol. 66, # 24 p. 8135 - 8138
反应条件
1: sodium-amalgam / in alkal. wss. Loesung
2: hydrogen chloride
3: potassium carbonate; methanol
View Scheme
参考文献
Robinson; Sugasawa
Journal of the Chemical Society, 1931 , p. 3163,3168
Journal of the Chemical Society, 1933 , p. 280
