反应条件
1: NaBH4 / tetrahydrofuran; H2O / 0.67 h / -6 - -2 °C 2: imidazole / dimethylformamide / 18 h / Ambient temperature 3: 91 percent / LiAlH4 / diethyl ether / 2 h / Ambient temperature 4: pyridine / CH2Cl2 / 15 h / 4 °C 5: NaI, NaHCO3 / acetone / 3 h / Heating 6: 1.) 1.66M BuLi / 1.) hexane, HMPA, THF, 0 deg C - 5 deg C, 40 min, 2.) hexane, HMPA, THF, r.t., 1 h 7: H2, quinoline / 5percent Pd/BaSO4 / methanol / 760 Torr 8: pyridine / CH2Cl2 / 14 h / 4 °C 9: LiBr, NaHCO3 / acetone / 24 h / Ambient temperature 10: 67 percent / KOH / methanol; aq. ethanol / 3 h / 65 °C 11: 91 percent / 1.0M tetrabutylammonium fluoride / tetrahydrofuran / 5 h / Ambient temperature 12: 97 percent / H2 / platinum oxide / hexane; diethyl ether; acetic acid / 96 h / 760 Torr View Scheme
参考文献
Mori, Kenji; Ogita, Haruhisa
Liebigs Annalen der Chemie, 1994 , # 11 p. 1065 - 1068
