2-氧代环己烷乙醛酸乙酯合成路线 （共 17 条）
反应条件
sodium ethanolate in ethanol T=20°C; 12 h;
参考文献
NANYANG TECHNOLOGICAL UNIVERSITY; YOON, Ho Sup; LIU, Xuewei; AMARAVADHI, Venkata, Krishna, Harikishore
Patent: WO2013/162469 A1, 2013 ;
Location in patent: Paragraph 00220; 00221 ;
反应条件
1: cyclohexanone With lithium hexamethyldisilazane in diethyl ether T=-78°C; 1 h; 2: oxalic acid diethyl ester in diethyl ether T=-78 - 20°C; 4 h; 3: With hydrogenchloride in diethyl ether; water Product distribution / selectivity;
参考文献
Lagu, Bharat; Liotta, Fina; Pan, Meng; Wachter, Michael P.; Xia, Mingde Xia
Patent: US2005/228034 A1, 2005 ;
Location in patent: Page/Page column 99-100 ;
US 20050228034 A1
反应条件
1: sodium; alcohol 2: HCl View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 350, p. 210
参考文献
Justus Liebigs Annalen der Chemie, , vol. 350, p. 210
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 88, p. 270
反应条件
ethanol Verseifung mit siedender alkoholischer Natronlauge;
参考文献
v. Auwers et al.
Justus Liebigs Annalen der Chemie, 1929 , vol. 469, p. 62
Full Text Show Details
v.Auwers; Wolter
Journal fuer Praktische Chemie (Leipzig), 1930 , vol. <2>126, p. 211
反应条件
1: N2H4*H2O; AcOH / 8 h / Heating 2: 53 percent / aq. NaOH / dioxane / 18 h / 20 °C View Scheme
参考文献
Van Herk; Brussee; Van den Nieuwendijk; Van der Klein; IJzerman; Stannek; Burmeister; Lorenzen
Journal of Medicinal Chemistry, 2003 , vol. 46, # 18 p. 3945 - 3951
反应条件
1: N2H4+H2O 2: palladium/charcoal; decalin View Scheme
参考文献
Ainsworth
Journal of the American Chemical Society, 1957 , vol. 79, p. 5242,5243
反应条件
hydrogenchloride; ethanol; hydroxylamine Erhitzen des Reaktionsprodukts mit wss. NaOH;
参考文献
Basu; Dhar
Journal of the Indian Chemical Society, 1946 , vol. 23, p. 189,191
反应条件
1: hydrazine hydrate; acetic acid / 0 °C / Reflux 2: hydrazine hydrate / ethanol / 36 h / Reflux View Scheme
参考文献
NANYANG TECHNOLOGICAL UNIVERSITY; YOON, Ho Sup; LIU, Xuewei; AMARAVADHI, Venkata, Krishna, Harikishore
Patent: WO2013/162469 A1, 2013 ;
