9-氯-1,2,3,4-四氢吖啶合成路线 (共 28 条)
反应条件
trichlorophosphate Cyclization; condensation; 2 h; Heating;
参考文献
Hu
Journal of Pharmacy and Pharmacology, 2001 , vol. 53, # 1 p. 83 - 88
Title/Abstract Full Text View citing articles Show Details
Hu, Ming-Kuan; Wu, Li-Ju; Hsiao, George; Yen, Mao-Hsiung
Journal of Medicinal Chemistry, 2002 , vol. 45, # 11 p. 2277 - 2282
参考文献
Solvay Pharmaceuticals B.V.
Patent: US2008/153867 A1, 2008 ;
Location in patent: Page/Page column 16 ;
US 20080153867 A1
反应条件
trichlorophosphate 3 h; Heating;
参考文献
Dorronsoro, Isabel; Alonso, Diana; Castro, Ana; Del Monte, Maria; Garcia-Palomero, Esther; Martinez, Ana
Archiv der Pharmazie, 2005 , vol. 338, # 1 p. 18 - 23
反应条件
copper(II) bis(trifluoromethanesulfonate) in 1,2-dichloro-ethane T=130°C; 12 h; Inert atmosphereSealed tube;
参考文献
Wang, Yong; Chen, Chao; Zhang, Shu; Lou, Zhenbang; Su, Xiang; Wen, Lirong; Li, Ming
Organic Letters, 2013 , vol. 15, # 18 p. 4794 - 4797
反应条件
trichlorophosphate in toluene T=20 - 100°C; 8 h;
参考文献
Tripathi; Verma; Pandey, Jyoti; Agarwal; Chaturvedi, Vinita; Manju; Srivastva; Gaikwad; Sinha
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 19 p. 5144 - 5147
反应条件
trichlorophosphate T=0 - 100°C; 0.833333 h;
参考文献
US2006/9451 A1, ;
Page/Page column 8 ;
US 20060009451 A1
反应条件
copper dichloride; isopentyl nitrite in acetonitrile T=65°C; Sandmeyer reaction; 2 h; Inert atmosphere;
参考文献
Da Silva, Daniel; Samadi, Abdelouahid; Chioua, Mourad; Do Carmo Carreiras, Maria; Marco-Contelles, Jose
Synthesis, 2010 , # 16 art. no. P05210SS, p. 2725 - 2730
反应条件
1: toluene / Reflux 2: trichlorophosphate / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 2 p. 763 - 770
反应条件
1: toluene / Reflux 2: trichlorophosphate / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 2 p. 763 - 770
European Journal of Medicinal Chemistry, , vol. 46, # 6 p. 2609 - 2616
参考文献
Journal of the Society of Chemical Industry, London, , vol. 64, p. 169,170
Journal of Organic Chemistry, , vol. 11, p. 359,360, 361
Zhurnal Obshchei Khimii, , vol. 7, p. 842,844
Chem. Zentralbl., , vol. 110, # I p. 1366