2,6-二氯异烟酸合成路线

2,6-二氯异烟酸合成路线（共 83 条）

5398-44-72,6-二氯异烟酸

6313-54-82-氯异烟酸

参考文献

Buechi et al.
Helvetica Chimica Acta, 1947 , vol. 30, p. 507,513

5398-44-72,6-二氯异烟酸+

7803-57-8水合肼

6313-54-82-氯异烟酸

参考文献

Thielepape; Spreckelsen
Chemische Berichte, 1922 , vol. 55, p. 2936

5398-44-72,6-二氯异烟酸

6313-55-92-氨基-6-氯-4-吡啶羧酸

参考文献

GLAXO GROUP LIMITED; BARTON, Nicholas Paul; CAMPOS, Sebastien Andre; CARR, Robin Arthur; HARLING, John David; SMITH, Ian Edward David
Patent: WO2012/35055 A1, 2012 ;
Location in patent: Page/Page column 129-130 ;
WO 2012/035055 A1

5398-44-72,6-二氯异烟酸

65287-34-52-氯吡啶-4-酰氯

参考文献

Buechi et al.
Helvetica Chimica Acta, 1947 , vol. 30, p. 507,513

5398-44-72,6-二氯异烟酸

6457-49-44-羟甲基哌啶

参考文献

Rabe
Journal fuer Praktische Chemie (Leipzig), 1938 , vol. <2> 151, p. 65,79

24424-99-5二碳酸二叔丁酯+

5398-44-72,6-二氯异烟酸

75308-46-22,6-二氯吡啶-4-甲酸叔丁酯

参考文献

McDermott, Todd S.; Bhagavatula, Lakshmi; Borchardt, Thomas B.; Engstrom, Kenneth M.; Gandarilla, Jorge; Kotecki, Brian J.; Kruger, Albert W.; Rozema, Michael J.; Sheikh, Ahmad Y.; Wagaw, Seble H.; Wittenberger, Steven J.
Organic Process Research and Development, 2009 , vol. 13, # 6 p. 1145 - 1155

5398-44-72,6-二氯异烟酸+

36805-97-7N,N-二甲基甲酰胺二叔丁基缩醛

75308-46-22,6-二氯吡啶-4-甲酸叔丁酯

参考文献

Schmidt, Gunther; Reber, Stefan; Bolli, Martin H.; Abele, Stefan
Organic Process Research and Development, 2012 , vol. 16, # 4 p. 595 - 604

5398-44-72,6-二氯异烟酸+

115-11-7异丁烯

75308-46-22,6-二氯吡啶-4-甲酸叔丁酯

参考文献

ELI LILLY AND COMPANY
Patent: WO2005/108358 A2, 2005 ;
Location in patent: Page/Page column 76 ;
WO 2005/108358 A2

71432-55-82-叔丁基-1,3-二异丙基异脲+

5398-44-72,6-二氯异烟酸