1,3-苯并噻唑-2,6-二胺合成路线 （共 7 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=20°C; P=2250.23 Torr; 2.5 h;
参考文献
US2009/233949 A1, ;
Page/Page column 10 ;
反应条件
ammonium hydroxide; thionyl chloride in water
参考文献
Archiv der Pharmazie (Weinheim, Germany), , p. 31,48
反应条件
hydrogenchloride; sodium nitrite anschliessende Einwirkung von heissem wss. CuCl auf das Reaktionsgemisch;
参考文献
Kaufmann
Archiv der Pharmazie (Weinheim, Germany), 1935 , vol. 273, p. 31,50
反应条件
in tetrahydrofuran
T=20°C; 7 h;
参考文献
MCR RESEARCH INC.
Patent: WO2004/14885 A1, 2004 ;
Location in patent: Page 28 ;
反应条件
1: tetrahydrofuran
2: aq. NaOH / tetrahydrofuran
View Scheme
参考文献
Patman, Joanne; Bhardwaj, Namrta; Ramnauth, Jailall; Annedi, Subhash C.; Renton, Paul; Maddaford, Shawn P.; Rakhit, Suman; Andrews, John S.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 9 p. 2540 - 2544
