反应条件
methanol; carbon monoxide; sodium hydride in methanol; N,N-dimethyl-formamide Irradiation (UV/VIS); soln. of aminocarbene in DMF is added to NaH at 0°C under Ar; after 10 min BuI is added, stirring for 15 h, addn. of NH4Cl, extn., drying, fitn., concn.; resulting intermediate is taken in MeOH, irradn. under 75 psi of CO for 15-24 h;; removing Cr(CO)6 by filtn.; filtrate is concd. in vacuo, dissolved in ether-hexane, photooxidized, filtn., evapn., radial chromy. yields amino ester; NMR, IR, elem. anal.;
参考文献
Hegedus, Louis S.; Schwindt, Mark A.; De Lombaert, Stephane; Imwinkelried, Rene
Journal of the American Chemical Society, 1990 , vol. 112, # 6 p. 2264 - 2273
