1: With methanol; (S)-2-carbomethoxypyrrolidine hydrochloride in water
T=20°C; Diels-Alder reaction; 12 h;
2: With water; trifluoroacetic acid in chloroform
T=20°C; 2 h; optical yield given as percent eeenantioselective reaction;
1: HCl / -78 °C
2: (i) MgCl2, K, THF, (ii) /BRN= 1900390/
4: LiAlH4
View Scheme
参考文献
Coe, Diane M.; Parry, David M.; Roberts, Stanley M.; Storer, Richard
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 10 p. 2373 - 2378