2,2-二苯基-4-哌啶戊腈合成路线 （共 5 条）
反应条件
1: α,α-diphenylacetonitrile With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in dimethyl sulfoxide
0.25 h;
2: 1-(2-chloro-propyl)-piperidine; hydrochloride in dimethyl sulfoxide
T=40°C; 1 h;
参考文献
Unterhalt; Coesfeld
Scientia Pharmaceutica, 2000 , vol. 68, # 3 p. 229 - 234
反应条件
sodium amide; benzene
参考文献
Bockmuehl; Ehrhart
Justus Liebigs Annalen der Chemie, 1949 , vol. 561, p. 52,76
Full Text Show Details
Ofner; Walton
Journal of the Chemical Society, 1950 , p. 2158,2162
Full Text Show Details
Kubota
Kumamoto Medical Journal, 1959 , vol. 12, p. 308,310
Chem.Abstr., 1960 , p. 24711
反应条件
1: nickel catalyst; ethanol / 80 - 100 °C / Hydrogenation
2: benzene; thionyl chloride
3: phenyl lithium; diethyl ether; diethylamine
View Scheme
参考文献
Bockmuehl; Ehrhart
Justus Liebigs Annalen der Chemie, 1949 , vol. 561, p. 52,76
反应条件
1: benzene; thionyl chloride
2: phenyl lithium; diethyl ether; diethylamine
View Scheme
参考文献
Bockmuehl; Ehrhart
Justus Liebigs Annalen der Chemie, 1949 , vol. 561, p. 52,76
参考文献
Ofner; Walton
Journal of the Chemical Society, 1950 , p. 2158,2162
