2-氯-4-哌啶-1-嘧啶合成路线 （共 7 条）
反应条件
in 1,4-dioxane
T=120°C; 1.5 h;
参考文献
Yoshida, Kenji; Taguchi, Masahiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 7 p. 919 - 922
反应条件
triethylamine in ethanol
T=20 - 25°C; 1 h;
参考文献
Del Corona; Signorelli; Manzardo; Pinzetta; Coppi
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 7 p. 729 - 733
反应条件
1: 91 percent / Et3N / dioxane / 3 h / 20 °C
2: aq. Na2CO3 / Bedford catalyst / 1,2-dimethoxy-ethane / 18 h / Heating
View Scheme
参考文献
Large, Jonathan M.; Clarke, Maria; Williamson, David M.; McDonald, Edward; Collins, Ian
Synlett, 2006 , # 6 p. 861 - 864
反应条件
sodium carbonate; Bedford's palladacycle catalyst in ethylene glycol dimethyl ether
Suzuki coupling reaction; 18 h; Heating;
参考文献
Large, Jonathan M.; Clarke, Maria; Williamson, David M.; McDonald, Edward; Collins, Ian
Synlett, 2006 , # 6 p. 861 - 864
反应条件
in 1,4-dioxane
T=120°C; 4 h;
参考文献
Yoshida, Kenji; Taguchi, Masahiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 7 p. 919 - 922
反应条件
in 1,4-dioxane
T=120°C; 6 h;
参考文献
Yoshida, Kenji; Taguchi, Masahiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 7 p. 919 - 922
反应条件
in 1,4-dioxane
T=120°C; 12 h;
参考文献
Yoshida, Kenji; Taguchi, Masahiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 7 p. 919 - 922
