water T=390°C; 0.5 h; Product distribution; Further Variations:ReagentsSolventsTemperaturesPressures;

<b>Multi-step reaction with 3 steps<br /> </b>1: 86 percent / tetrahydrofuran / 67 h / 0 - 20 &deg;C<br />2: 81 percent / Et₃N; 4-(dimethylamino)pyridine / CH₂Cl₂ / 4 h / 0 - 20 &deg;C<br />3: 87 percent / Pd(dba)2 / tetrahydrofuran / 6 h / 20 &deg;C<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '15732764', constants.ctx, '0')">palladium (II) trifluoroacetate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587218', constants.ctx, '0')">oxygen</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '741937', constants.ctx, '0')">acetylacetone</a>&nbsp;<b>in</b>&nbsp; neat (no solvent)<br />T=40&deg;C;&nbsp;P=760.051&nbsp;Torr;&nbsp;72&nbsp;h;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1209227', constants.ctx, '0')">n-butyllithium</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3556712', constants.ctx, '0')">potassium <i>tert</i>-butylate</a> <br />&nbsp;1.) THP, hexane, a) 0 deg C, 3 h, b) -25 deg C, 72 h, 2.) THP, from -75 deg C to 25 deg C;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;