2,6-二羟基-3-氰基-4-甲基吡啶合成路线 （共 31 条）
参考文献
Journal of the Indian Chemical Society, , vol. 8, p. 323
Chem. Zentralbl., , vol. 102, # II p. 2328
参考文献
Journal of the Indian Chemical Society, , vol. 8, p. 323
Chem. Zentralbl., , vol. 102, # II p. 2328
反应条件
1: 98 percent / POCl3 / 6 h / 120 °C 2: 93 percent / aq. H2SO4 / 6 h / 98 °C View Scheme
参考文献
Dyadyuchenko; Strelkov; Mikhailichenko; Zaplishny
Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 3 p. 308 - 314
反应条件
hydrogenchloride T=150 - 160°C;
参考文献
Basu
Journal of the Indian Chemical Society, 1931 , vol. 8, p. 323
Chem. Zentralbl., 1931 , vol. 102, # II p. 2328
参考文献
Gibson; Simonsen
Journal of the Chemical Society, 1929 , p. 1075
Full Text Show Details
Guareschi
Atti della Accademia delle Scienze di Torino, Classe di Scienze Fisiche, Matematiche e Naturali, vol. 36, p. 453
Chem. Zentralbl., 1901 , vol. 72, # I p. 822
反应条件
1: 1.) POCl3, 2.) H2, PdCl2-AcONa / 1.) 180 deg C, 4 h, 2.) 40 deg C, 3 atm, 12 h 2: 1.) DIBAL, 2.) 1 N HCl / 1.) CH2Cl2/hexane, from -78 deg C, to RT, 2.) 1 h View Scheme
参考文献
Konno, Katsuhiro; Qin, Guo-wei; Nakanishi, Koji
Heterocycles, 1990 , vol. 30, # 1 p. 247 - 251
反应条件
silver carbonate in benzene
参考文献
Mal, Prasenjit; Lourderaj; Parveen; Venugopalan; Moorthy, J. Narasimha; Sathyamurthy
Journal of Organic Chemistry, 2003 , vol. 68, # 9 p. 3446 - 3453
参考文献
Janin, Yves L.; Huel, Christiane; Flad, Genevieve; Thirot, Sylvie
European Journal of Organic Chemistry, 2002 , # 11 p. 1763 - 1769
反应条件
trichlorophosphate T=200°C; 7 h;
参考文献
Dyadyuchenko; Strelkov; Mikhailichenko; Zaplishny
Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 3 p. 308 - 314
反应条件
sodium carbonate; trichlorophosphate in quinoline
参考文献
Cassella Aktiengesellschaft
Patent: US4325870 A1, 1982 ;
