4′-氯-3′-硝基苯乙酮合成路线 （共 32 条）
反应条件
tetra(n-butyl)ammonium tribromide in tetrahydrofuran T=20°C; 24 h;
参考文献
Shionogi and Co., Ltd.
Patent: WO2005/121132 A1, 2005 ;
Location in patent: Page/Page column 234-235 ;
反应条件
in tetrahydrofuran T=20 - 80°C; 26 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GmbH; BOEHRINGER INGELHEIM PHARMA GmbH and CO KG
Patent: WO2005/80388 A1, 2005 ;
Location in patent: Page/Page column 74 ;
WO 2005/080388 A1
反应条件
hydrogenchloride; stannous chloride dihydrate in methanol; water Reflux;
参考文献
Aissaoui, Hamed; Koberstein, Ralf; Zumbrunn, Cornelia; Gatfield, John; Brisbare-Roch, Catherine; Jenck, Francois; Treiber, Alexander; Boss, Christoph
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 21 p. 5729 - 5733
反应条件
sodium hydroxide; palladium dichloride in anhydrous xylene
参考文献
Hoechst Aktiengesellschaft
Patent: US5744643 A1, 1998 ;
反应条件
carbon monoxide; hexasulfonated 2,2'-bis-diphenylphosphinomethylene binaphthyl; palladium dichloride in water; xylene T=100°C; P=90007.2 Torr; 20 h; Yields of byproduct given;
参考文献
Tafesh, Ahmed M.; Beller, Matthias
Tetrahedron Letters, 1995 , vol. 36, # 51 p. 9305 - 9308
反应条件
hydrogenchloride in methanol
参考文献
Asahi Kasei Kogyo Kabushiki Kaisha
Patent: US6037362 A1, 2000 ;
参考文献
Leonard; Boyd
Journal of Organic Chemistry, 1946 , vol. 11, p. 405,412
反应条件
in isopropyl alcohol 8 h; Heating;
参考文献
Varma, Rajendra S; Sarin, Simi; Chatterjee, R K
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1992 , vol. 31, # 10 p. 711 - 713
反应条件
/BRN= 102438/ in dimethyl sulfoxide T=45°C; Rate constant;
参考文献
Kavalek,J. et al.
Collection of Czechoslovak Chemical Communications, 1971 , vol. 36, p. 209 - 217
参考文献
Bunnett et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 642,644
