5-溴-4-甲基-2-噻吩羧酸甲酯合成路线 (共 4 条)
参考文献
Agouron Pharmaceuticals, Inc.
Patent: US5608082 A1, 1997 ;
反应条件
potassium carbonate in N-methyl-acetamide
反应条件
acetic acid in water
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5840917 A1, 1998 ;
反应条件
1: With sodium hydroxide in ethanol; water
T=80°C; 2 h;
2: With hydrogenchloride in dichloromethane; water
参考文献
MEDIVIR AB
Patent: WO2007/6714 A1, 2007 ;
Location in patent: Page/Page column 106-107 ;