4-(四氢-2H-吡喃-2-基氧基)丁醛合成路线 （共 19 条）
参考文献
Ghosh, Nayan; Nayak, Sanatan; Sahoo, Akhila K.
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 500 - 511
参考文献
Crisostomo, Fernando R. P.; Martin, Tomas; Martin, Victor S.
Organic Letters, 2004 , vol. 6, # 4 p. 565 - 568
反应条件
potassium tert-butylate; lithium diisopropyl amide
1.)-78 deg C,in THF, diluted with ether, 2.) in THF, 1h, at room temperature; Multistep reaction. Title compound not separated from byproducts;
参考文献
Ley, Steven V.; Lygo, Barry
Tetrahedron Letters, 1984 , vol. 25, # 1 p. 113 - 116
反应条件
potassium tert-butylate; lithium diisopropyl amide
1.)-78 deg C,in THF, diluted with ether, 2.) in THF, 1h, at room temperature; Multistep reaction. Title compound not separated from byproducts;
参考文献
Ley, Steven V.; Lygo, Barry
Tetrahedron Letters, 1984 , vol. 25, # 1 p. 113 - 116
反应条件
Collins oxidation agent
1.) ether, 0 deg C -> room temperature, 30 min, 2.) dichloromethane, room temperature, 2 h; Yield given. Multistep reaction;
参考文献
Doherty, Annette M.; Ley, Steven V.; Lygo, Barry; Williams, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 1371 - 1378
反应条件
1: benzene
2: LiAl(OC2H5)2H2 / diethyl ether
3: pyridinium chlorochromate / CH2Cl2
View Scheme
参考文献
Parker, Kathlyn A.; Farmar, James G.
Journal of Organic Chemistry, 1986 , vol. 51, # 21 p. 4023 - 4028
参考文献
Matikainen, Jorma; Kaltia, Seppo; Haemaelaeinen, Markku; Hase, Tapio
Tetrahedron, 1997 , vol. 53, # 12 p. 4531 - 4538
反应条件
in tetrahydrofuran; diethyl ether
T=-78°C; 0.25 h;
参考文献
Crevisy, Christophe; Couturier, Michel; Dugave, Christophe; Dory, Yves L.; Deslongchamps, Pierre
Bulletin de la Societe Chimique de France, 1995 , vol. 132, # 4 p. 360 - 370
反应条件
in tetrahydrofuran
1) 2 h, reflux, 2) 12 h, r.t.;
参考文献
Bestmann, Hans Juergen; Li, Kedong
Chemische Berichte, 1982 , vol. 115, # 2 p. 828 - 831
