alpha-环己基噻吩-3-乙腈合成路线 (共 5 条)
反应条件
hydrogenchloride in ethanol; cyclohexane; benzene
参考文献
Labaz
Patent: US4108865 A1, 1978 ;
反应条件
hydrogenchloride; nitrogen in ethanol; cyclohexane; benzene
参考文献
Labaz
Patent: US4108865 A1, 1978 ;
反应条件
sodium tetrahydroborate in ethanol
18 h; Heating;
参考文献
De Cointet; Grossi; Pigerol; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 3 p. 223 - 227
反应条件
1: 73 percent / sodium ethylate / ethanol / 8 h / 4 °C
2: 80 percent / sodium borohydride / ethanol / 18 h / Heating
View Scheme
参考文献
De Cointet; Grossi; Pigerol; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 3 p. 223 - 227
反应条件
1: 73 percent / sodium ethylate / ethanol / 8 h / 4 °C
2: 80 percent / sodium borohydride / ethanol / 18 h / Heating
View Scheme
参考文献
De Cointet; Grossi; Pigerol; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 3 p. 223 - 227