3,3'-二氨基二丙基胺合成路线 （共 53 条）
反应条件
[σ:η1:η5-(OCH2)(Me2NCH2)C2B9H9]Ti-(NMe2) in toluene
T=115°C; 240 h;
参考文献
Shen, Hao; Wang, Yang; Xie, Zuowei
Organic Letters, 2011 , vol. 13, # 17 p. 4562 - 4565
反应条件
sodium cyanoborohydride; acetic acid in methanol
T=20°C; 24 h;
参考文献
Vincent, Stephane P; Lehn, Jean-Marie; Lazarte, Jaime; Nicolau, Claude
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 9 p. 2825 - 2834
反应条件
in diethyl ether; dimethyl sulfoxide
1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Hansen, J. B.; Nielsen, M. C.; Ehrbar, U.; Buchardt, O.
Synthesis, 1982 , # 5 p. 404 - 405
反应条件
in tetrahydrofuran
T=0°C; 24 h; Inert atmosphere;
参考文献
Abe, Yukiko; Nakagawa, Osamu; Yamaguchi, Rie; Sasaki, Shigeki
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 11 p. 3470 - 3479
反应条件
mono-BOC protection;
参考文献
Sasaki, Hideaki; Sasaki, Shigeki
Chemical Communications, 2013 , vol. 49, # 79 p. 9024 - 9026
反应条件
in methanol
T=20°C; 120 h; regioselective reaction;
参考文献
Solvhoj, Amanda B.; Tortzen, Christian; Christensen, Jorn B.
Organic Preparations and Procedures International, 2012 , vol. 44, # 4 p. 397 - 400
反应条件
in diethyl ether; dimethyl sulfoxide
1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Hansen, J. B.; Nielsen, M. C.; Ehrbar, U.; Buchardt, O.
Synthesis, 1982 , # 5 p. 404 - 405
参考文献
Bradshaw, Jerald S.; Krakowiak, Krzysztof E.; An, Haovyn; Izatt, Reed M.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 6 p. 1429 - 1432
反应条件
2: 1.) NaH / 1) DMF; 2) DMF, 110 deg C
3: aq. HBr, AcOH, phenol / 14 h / 80 °C
View Scheme
参考文献
Dietrich, B.; Hosseini, M. W.; Lehn, J. M.; Sessions, R. B.
Journal of the American Chemical Society, 1981 , vol. 103, # 5 p. 1282 - 1283
参考文献
Bayer A.G.
Patent: DE2551483 , 1977 ;
Chem.Abstr., 1977 , vol. 87, # 67862
