(2R)-2-(3-苯甲酰基苯基)丙酸合成路线 （共 22 条）
反应条件
Thermotoga maritima esterase Tm1160 in aq. acetate buffer T=70°C; pH=5.5; 32 h; Enzymatic reaction; enantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 85-86, p. 23 - 30
反应条件
1: Novozyme 435 / toluene / 2 h / 45 °C 2: 360 mg / Novozyme 435 / acetonitrile; H2O / 45 h / 45 °C View Scheme
参考文献
Physical Chemistry Chemical Physics, , vol. 7, # 23 p. 4002 - 4008
反应条件
immobilized Lipozymereg; in 1,4-dioxane; water T=25°C; 96 h; Enzymatic reaction; optical yield given as percent ee;
参考文献
Wang, Hai-Yang; Li, Chao; Wang, Na; Li, Kun; Feng, Xing-Wen; He, Ting; Yu, Xiao-Qi
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 5 p. 1905 - 1910
反应条件
hydrogenchloride; acetic acid in water T=120°C; 2.5 h; optical yield given as percent ee;
参考文献
Andreu, Inmaculada; Morera, Isabel M.; Bosca, Francisco; Sanchez, Laura; Camps, Pelayo; Miranda, Miguel A.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 5 p. 860 - 867
反应条件
Birman's catalyst; 4-methoxybenzoic anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 35 p. 5887 - 5890
反应条件
4-methoxybenzoic anhydride; N-ethyl-N,N-diisopropylamine; Birman's catalyst in dichloromethane T=20°C; 12 h; Resolution of racemate; Product distribution / selectivity;
参考文献
US2010/234610 A1, ;
Page/Page column 12-13 ;
反应条件
sodium hydroxide in water T=40°C; 7.55 h; titrisol buffer pH 8, carboxylesterase NP; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 111, # 11 p. 490 - 495
反应条件
sodium carbonate in methanol; water 2 h; Ambient temperature;
参考文献
Calmes, Monique; Daunis, Jacques; Jacquier, Robert; Natt, Francois
Tetrahedron, 1994 , vol. 50, # 23 p. 6875 - 6880
反应条件
phosphate buffer; sodium lauryl sulfate; vancomycin T=20°C; electrophoretic enantioseparations, various substrates; Product distribution;
参考文献
Analytical chemistry, , vol. 67, # 13 p. 2088 - 2095
反应条件
water T=40°C; 40 h; Candida rugosa lipase, pH 5; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 117, # 26 p. 6845 - 6852
