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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
56366-26-8
合成路线
(共 11 条)
100-17-4
4-硝基苯甲醚
+
536-74-3
苯乙炔
→
反应条件
56366-26-8
反应条件
carbon monoxide; 4 A molecular sieve; [(η5-C5Me5)Ru(CO)2]2 in 1,4-dioxane T=170°C; P=38787.1 Torr; 48 h;
参考文献
Penoni, Andrea; Nicholas, Kenneth M.
Chemical Communications, 2002 , # 5 p. 484 - 485
1006-94-6
5-甲氧基吲哚
→
反应条件
56366-26-8
反应条件
2,6-di-tert-butyl-pyridine; copper(II) bis(trifluoromethanesulfonate) in dichloromethane T=20°C; 14 h;
参考文献
Phipps, Robert J.; Grimster, Neil P.; Gaunt, Matthew J.
Journal of the American Chemical Society, 2008 , vol. 130, # 26 p. 8172 - 8174
1006-94-6
5-甲氧基吲哚
+
108-94-1
环己酮
→
反应条件
56366-26-8
反应条件
palladium (II) trifluoroacetate; oxygen; bis[2-(diphenylphosphino)phenyl] ether in toluene T=140°C; 30 h; regioselective reaction;
参考文献
Chen, Shanping; Liao, Yunfeng; Zhao, Feng; Qi, Hongrui; Liu, Saiwen; Deng, Guo-Jun
Organic Letters, 2014 , vol. 16, # 6 p. 1618 - 1621
1006-94-6
5-甲氧基吲哚
+
108-86-1
溴代苯
→
反应条件
56366-26-8
反应条件
potassium carbonate; [(t-Bu)2P(OH)]2PdCl2 in 1,4-dioxane 24 h; Heating;
参考文献
Zhang, Zhiqiang; Hu, Zhizhi; Yu, Zhixiao; Lei, Peng; Chi, Haijun; Wang, Yue; He, Ren
Tetrahedron Letters, 2007 , vol. 48, # 13 p. 2415 - 2419
1006-94-6
5-甲氧基吲哚
+
108-86-1
溴代苯
→
反应条件
56366-26-8
+
5883-96-5
5-甲氧基-2-苯基-1H-吲哚
反应条件
lithium hydroxide hydrate; palladium diacetate; bis(1,1-diphenylphosphino)methane in water T=110°C; 18 h; regioselective reaction;
参考文献
Joucla, Lionel; Batail, Nelly; Djakovitch, Laurent
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 17 p. 2929 - 2936
1516-21-8
4-亚硝基苯甲醚
+
536-74-3
苯乙炔
→
反应条件
56366-26-8
反应条件
CuCl2*2H2O; copper in 1,4-dioxane T=100°C; 5 h; Inert atmosphere; regioselective reaction;
参考文献
Murru, Siva; Gallo, August A.; Srivastava, Radhey S.
European Journal of Organic Chemistry, 2011 , # 11 p. 2035 - 2038
1006-94-6
5-甲氧基吲哚
+
100-63-0
苯肼
→
反应条件
56366-26-8
反应条件
1,10-phenanthroline; palladium diacetate; trifluoroacetic acid in chlorobenzene T=100°C; 12 h;
参考文献
Chen, Yongxin; Guo, Shuaibo; Li, Kangning; Qu, Jinpeng; Yuan, Hua; Hua, Qiuru; Chen, Baohua
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 711 - 715
935-50-2
4,4-二甲氧基-2,5-环己二烯-1-酮
+
5470-36-0
→
反应条件
56366-26-8
反应条件
pyridine in chloroform T=90°C; 6 h; Inert atmosphere;
参考文献
Zhang, Jinzhu; Yin, Zhiwei; Leonard, Patrick; Wu, Jing; Sioson, Kate; Liu, Che; Lapo, Robert; Zheng, Shengping
Angewandte Chemie - International Edition, 2013 , vol. 52, # 6 p. 1753 - 1757
Angew. Chem., 2013 , vol. 125, # 6 p. 1797 - 1801,5
1190709-19-3
→
反应条件
56366-26-8
反应条件
potassium carbonate in methanol
参考文献
Leboho, Tlabo C.; Michael, Joseph P.; van Otterlo, Willem A.L.; van Vuuren, Sandy F.; de Koning, Charles B.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 17 p. 4948 - 4951
103-63-9
(2-溴乙基)苯
→
反应条件
56366-26-8
反应条件
1.1: hydrazine hydrate / ethanol / 2 h / |Reflux; |Inert atmosphere 1.2: |Inert atmosphere 2.1: pyridine / chloroform / 6 h / 90 °C / |Inert atmosphere View Scheme
参考文献
Zhang, Jinzhu; Yin, Zhiwei; Leonard, Patrick; Wu, Jing; Sioson, Kate; Liu, Che; Lapo, Robert; Zheng, Shengping
Angewandte Chemie - International Edition, 2013 , vol. 52, # 6 p. 1753 - 1757
Angew. Chem., 2013 , vol. 125, # 6 p. 1797 - 1801,5
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