2,4-二甲基-3-戊酮合成路线 （共 349 条）
反应条件
tetrahydrofuran in toluene
T=0°C; Grignard reaction; addition; reduction; Product distribution; Further Variations:Reagents;
参考文献
Tuulmets, Ants; Sassian, Meeri
Journal of Organometallic Chemistry, 1999 , vol. 586, # 2 p. 145 - 149
反应条件
tetrahydrofuran in toluene
T=0°C; Grignard reaction; addition; reduction; Product distribution; Further Variations:Reagents;
参考文献
Tuulmets, Ants; Sassian, Meeri
Journal of Organometallic Chemistry, 1999 , vol. 586, # 2 p. 145 - 149
反应条件
hydrogen
P=760 Torr; Irradiation; Yield given;
参考文献
Boojamra, Constantine G.; Crabtree, Robert H.; Ferguson, Richard R.; Muedas, Cesar A.
Tetrahedron Letters, 1989 , vol. 30, # 41 p. 5583 - 5586
反应条件
titanium(III) chloride in tetrahydrofuran
参考文献
Nishida,S.; Kataoka,F.
Journal of Organic Chemistry, 1978 , vol. 43, p. 1612 - 1613
反应条件
1: (i) EtMgBr, (ii) /BRN= 773782/
2: 330 °C
View Scheme
参考文献
Favorskaya,I.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, p. 789 - 792,806 - 808
参考文献
Whitmore; Laughlin
Journal of the American Chemical Society, 1932 , vol. 54, p. 4392
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Roberts; Green
Journal of the American Chemical Society, 1946 , vol. 68, p. 214
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Allen; Richmond
Journal of Organic Chemistry, 1937 , vol. 2, p. 222,224
反应条件
(i) dioxane, ClCH2CH2Cl, (ii) /BRN= 773782/, (iii) (heating); Multistep reaction;
参考文献
Hofmann,K.; Simchen,G.
Synthesis, 1979 , p. 699 - 700
反应条件
Yield given. Multistep reaction;
参考文献
Hofmann, Karin; Simchen, Gerhard
Liebigs Annalen der Chemie, 1984 , # 1 p. 39 - 47
反应条件
1: toluene-4-sulfonic acid / water / 48 h / 120 °C
2: indium(III) chloride; trimethylsilyl bromide / 1,2-dichloro-ethane / 2 h / Reflux; Inert atmosphere
View Scheme
参考文献
Onishi, Yoshiharu; Nishimoto, Yoshihiro; Yasuda, Makoto; Baba, Akio
Chemistry Letters, 2011 , vol. 40, # 11 p. 1223 - 1225
反应条件
sodium hydroxide; tetrabutylammomium bromide in water
参考文献
Haarmann and Reimer GmbH
Patent: US6252120 B1, 2001 ;
