phosphorous acid trimethyl ester in methanol T=25°C; Rate constant;

1: (i) nBuLi, iPr2NH, hexane, THF, (ii) Ph2S2 2: HgCl2 / acetonitrile; H2O View Scheme

(i) nBuLi, iPr2NH, hexane, THF, (ii) Ph2S2; Multistep reaction;

<b>Multi-step reaction with 2 steps<br /> </b>1: 1.) n-BuLi / 1.) THF, hexane, - 78 deg C<br />2: KH / tetrahydrofuran / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 1.) diethylamine, n-BuLi / 1.) pentane, THF, 10 min, -10 deg C, 2.) 5 h, room temp.<br />2: 1.) n-BuLi / 1.) THF, hexane, - 78 deg C<br />3: KH / tetrahydrofuran / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 1.) diethylamine, n-BuLi / 1.) pentane, THF, 10 min, -10 deg C, 2.) 5 h, room temp.<br />2: 1.) n-BuLi / 1.) THF, hexane, - 78 deg C<br />3: KH / tetrahydrofuran / Ambient temperature<br /> <br /> &nbsp;

&nbsp;(i) nBuLi, hexane, THF, (ii) /BRN= 774156/;&nbsp;&nbsp;Multistep reaction;&nbsp;<br /> &nbsp;