反应条件
1: 1.) NaH / 1.) DMSO, RT, 1 h, 2.) DMSO, 2.5 h 2: 67 percent / NaI, glacial AcOH / tetrahydrofuran; methanol / a) reflux, 6 h, b) RT, overnight 3: 51 percent / H2, NaOAc / 5percent Pd/C / methanol; tetrahydrofuran / 18 h View Scheme
参考文献
Hogenkamp, Derk J.; Tahir, S. Hasan; Hawkinson, Jon E.; Upasani, Ravi B.; Alauddin, Mian; Kimbrough, Catherine L.; Acosta-Burruel, Manuel; Whittemore; Woodward; Lan, Nancy C.; Gee, Kelvin W.; Bolger, Michael B.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 1 p. 61 - 72
