1: With potassium hydroxide in methanol T=20°C; 19.5 h; 2: With sodium hydroxide in water T=20°C; 18 h;

potassium hydroxide; sodium hydroxide in methanol; (2S)-N-methyl-1-phenylpropan-2-amine hydrate

1: With sodium hydroxide in ethanol; water T=100°C; Stetter cyclocondensation reaction; 0.333333 h; microwave irradiation; 2: With hydrogenchloride T=110°C; 0.333333 h; microwave irradiation; Further stages.;

sulfuric acid in water 3 h; Heating; Yield given;

1: 100 percent / KOH / methanol / Ambient temperature; overnight 2: 1M H2SO4 / H2O / 3 h / Heating View Scheme

hydrogenchloride; potassium hydroxide 1.) methanol, 2.) 90-100 deg C, 2 h; Yield given. Multistep reaction;

1: 1) ammonium carbonate, 2) KOH / 1) diethylene glycol, 120-130 deg C, 1h, 2) 195 deg C, 3h 2: 1a) BuLi / 1a) THF, hexane, -70 deg C, 1b) 0 deg C, 1h, 2) THF, -40 deg C 3: molsieves (3 Angstroem), DDQ / toluene / Heating; one night 4: 89 percent Chromat. / 3M NaOH / ethanol / 1) 0 deg C, 2) r.t., 3h 5: 90 percent / transformed Escherichia coli cells View Scheme

p-toluenesulfonic acid monohydrate in methanol; ethyl acetate

in methanol T=0 - 20°C;

sulfuric acid 16 h; Heating;