5-甲基-4-硝基噻吩-2-羧酸甲酯合成路线 （共 14 条）
反应条件
sulfuric acid
T=20°C; Heating / reflux;
参考文献
ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA
Patent: WO2006/119975 A1, 2006 ;
Location in patent: Page/Page column 37 ;
反应条件
sulfuric acid; nitric acid
T=0 - 5°C; 0.5 h;
参考文献
Japan Tobacco Inc.
Patent: EP1688420 A1, 2006 ;
Location in patent: Page/Page column 131 ;
反应条件
(NH4)2S2O8; silver nitrate in water; acetonitrile
0.5 h; Heating;
参考文献
Cogolli, Pietro; Maiolo, Filippo; Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1331 - 1335
反应条件
(NH4)2S2O8; silver nitrate in water; acetonitrile
0.5 h; Heating;
参考文献
Cogolli, Pietro; Maiolo, Filippo; Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1331 - 1335
反应条件
1: nitric acid/acetic anhydride / 0.5 h / -10 °C
2: 50 percent / (NH4)2S2O8 / AgNO3 / acetonitrile; H2O / 0.5 h / Heating
View Scheme
参考文献
Cogolli, Pietro; Maiolo, Filippo; Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1331 - 1335
反应条件
1: tetrabutylammonium permanganate / pyridine
3: 50 percent / (NH4)2S2O8 / AgNO3 / acetonitrile; H2O / 0.5 h / Heating
View Scheme
参考文献
Cogolli, Pietro; Maiolo, Filippo; Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1331 - 1335
反应条件
2: 50 percent / (NH4)2S2O8 / AgNO3 / acetonitrile; H2O / 0.5 h / Heating
View Scheme
参考文献
Cogolli, Pietro; Maiolo, Filippo; Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1331 - 1335
反应条件
1: hydrogen chloride
2: nitric acid; acetic acid anhydride
View Scheme
参考文献
Rinkes
Recueil des Travaux Chimiques des Pays-Bas, 1933 , vol. 52, p. 538,547
反应条件
1: 50 percent / cc H2SO4/cc HNO3 / 0.5 h
2: 35 percent / (NH4)2S2O8 / AgNO3 / acetonitrile; H2O / 0.5 h / Heating
View Scheme
参考文献
Cogolli, Pietro; Maiolo, Filippo; Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1980 , p. 1331 - 1335
反应条件
1: magnesium; diethyl ether / anschliessend mit Kohlendioxid behandeln
2: hydrogen chloride
3: nitric acid; acetic acid anhydride
View Scheme
参考文献
Rinkes
Recueil des Travaux Chimiques des Pays-Bas, 1933 , vol. 52, p. 538,547
