1-(1-环己烯-1-基)-2-甲基-1-丙酮合成路线 （共 7 条）
反应条件
potassium hydroxide; zinc
T=15 - 20°C; 1) CH2Cl2, 2) MeOH;
参考文献
Shono, Tatsuya; Nishiguchi, Ikuzo; Sasaki, Manji; Ikeda, Haruhiko; Kurita, Makoto
Journal of Organic Chemistry, 1983 , vol. 48, # 15 p. 2503 - 2505
反应条件
in hydrogenchloride; diethyl ether
T=20°C; shake for 1-5 min;
参考文献
Moskal, Janusz; Leusen, Albert M. van
Tetrahedron Letters, 1984 , vol. 25, # 24 p. 2585 - 2588
反应条件
magnesium chloride in propan-1-ol
1.5 h; Heating;
参考文献
Satoh, Tsuyoshi; Sugimoto, Atsushi; Yamakawa, Koji
Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 11 p. 4632 - 4636
反应条件
2: 32 percent / 1) t-BuOK / 1,2-dimethoxy-ethane / 1) -30 deg C, 2) -30 to 20 deg C, 1 h
3: 90 percent / diethyl ether; aq. HCl / 20 °C / shake for 1-5 min
View Scheme
参考文献
Moskal, Janusz; Leusen, Albert M. van
Tetrahedron Letters, 1984 , vol. 25, # 24 p. 2585 - 2588
反应条件
1: 32 percent / 1) t-BuOK / 1,2-dimethoxy-ethane / 1) -30 deg C, 2) -30 to 20 deg C, 1 h
2: 90 percent / diethyl ether; aq. HCl / 20 °C / shake for 1-5 min
View Scheme
参考文献
Moskal, Janusz; Leusen, Albert M. van
Tetrahedron Letters, 1984 , vol. 25, # 24 p. 2585 - 2588
反应条件
(i) LDA, HMPT, THF, (ii) O2, (iii) aq. Na2SO3, NaOH; Multistep reaction;
参考文献
Wroble,R.R.; Watt,D.S.
Journal of Organic Chemistry, 1976 , vol. 41, p. 2939 - 2940
反应条件
1: NaNH2
2: (i) Zn, AcOH, aq. HCl, (ii) Pd-C
View Scheme
参考文献
Reisse,A. et al.
Bulletin de la Societe Chimique de France, 1970 , p. 742 - 746
