吡啶-2-基(吡啶-3-基)甲酮合成路线 （共 6 条）
反应条件
1: 2-bromo-pyridine With n-butyllithium in diethyl ether; hexane
T=-50°C; 0.5 h;
2: pyridine-3-carboxylic acid methyl ester in diethyl ether; hexane
T=-90°C; 1 h;
参考文献
Chen, Xu-Dong; Du, Miao; Mak, Thomas C. W.
Chemical Communications, 2005 , # 35 p. 4417 - 4419
反应条件
1: 3-bromo-pyridine With n-butyllithium in tetrahydrofuran; diethyl ether; hexane
T=-90°C; 0.25 h;
2: 2-Pyridinecarboxylic acid methyl ester in various solvents
T=-110 - 20°C; 4 h;
参考文献
Popova, I. S.; Formanovsky, A. A.; Mikhura, I. V.
Russian Chemical Bulletin, 2002 , vol. 51, # 3 p. 540 - 543
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 2002 , # 3 p. 501 - 504
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine
T=140°C; Inert atmosphere;
参考文献
Abarca, Belen; Adam, Rosa; Ballesteros, Rafael; Chiassai, Leonardo; Gamon, Cristina
Arkivoc, 2012 , vol. 2012, # 9 p. 229 - 241
参考文献
Henze; Knowles
Journal of Organic Chemistry, 1954 , vol. 19, p. 1127,1129
反应条件
in tetrahydrofuran
1 h; Inert atmosphere;
参考文献
Rao, G. Venkateswara; Swamy, B. Narayana; Kumar, P. Hareesh; Reddy, G. Chandrasekara
Synthetic Communications, 2009 , vol. 39, # 10 p. 1835 - 1846
反应条件
hydroxylamine hydrochloride; sodium hydroxide in ethanol; water
Reflux;
参考文献
Argyle, Victoria J.; Woods, Laura M.; Roxburgh, Marina; Hanton, Lyall R.
CrystEngComm, 2013 , vol. 15, # 1 p. 120 - 134
