Alpha,Alpha-二氯苯丙酮合成路线 （共 20 条）
参考文献
SANOFI and Industria Chimica Prodotti FRANCIS S.p.A.
Patent: US4713485 A1, 1987 ;
反应条件
1: sulfur / benzene / 1 h / 25 - 60 °C 2: dilute hydrochloric acid View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 21, # 10 p. 1961 - 1964
Zhurnal Organicheskoi Khimii, , vol. 21, # 10 p. 2143 - 2147
反应条件
in isopropyl alcohol Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 45, # 14 p. 2803 - 2813
反应条件
hydrogenchloride; Oxonereg; in N,N-dimethyl-formamide
T=20 - 25°C; 2 h;
参考文献
Kim, Kye Kwang; Kim, Jae Nyoung; Kim, Kyoung Mahn; Kim, Hyoung Rae; Ryu, Eung K.
Chemistry Letters, 1992 , # 4 p. 603 - 604
反应条件
in N,N-dimethyl-formamide
参考文献
SANOFI and Industria Chimica Prodotti FRANCIS S.p.A.
Patent: US4713485 A1, 1987 ;
反应条件
1: anhydrous dichloroethane With N,N,N',N',N'',N''-hexamethylphosphoric triamide; n-butyllithium in tetrahydrofuran; diethyl ether; hexane
T=-100°C; Metallation; 0.5 h;
2: benzoic acid methyl ester in diethyl ether
T=-78°C; Alkylation; 0.75 h;
参考文献
Shiina, Isamu; Imai, Yumiko; Kagayama, Akifumi; Mukaiyama, Teruaki
Chemistry Letters, 2000 , # 2 p. 190 - 191
反应条件
chlorine in N,N-dimethyl-formamide
T=90 - 95°C; 0.5 h;
参考文献
Kimpe, Norbert De; Verhe, Roland; Buyck, Laurent De; Schamp, Niceas
Journal of Organic Chemistry, 1980 , vol. 45, # 14 p. 2803 - 2813
反应条件
hydrogenchloride in dichloromethane
2 h; Heating;
参考文献
Kimpe, Norbert De; Coppens, Wim; Welch, John; Corte, Bart De
Synthesis, 1990 , # 8 p. 675 - 677
反应条件
manganese triacetate; lithium chloride in acetic acid
3 h; Heating; Product distributionMechanism;
参考文献
Tsuruta, Takehiko; Harada, Tetsuya; Nishino, Hiroshi; Kurosawa, Kazu
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 1 p. 142 - 145
反应条件
antimony(V) pentachloride in tetrachloromethane
4 h; Heating;
参考文献
Kim, Kil-Joong; Kim, Kyongtae
Tetrahedron Letters, 1997 , vol. 38, # 24 p. 4227 - 4230
