乙酰溴-α-D-葡萄糖合成路线 （共 502 条）
反应条件
Ag(1+)*C14H24AgN4O2(1+)*2Cl(1-) in acetonitrile T=25°C; 3 h; Darkness; stereoselective reaction;
参考文献
Talisman, Ian J.; Kumar, Vineet; Deschamps, Jeffrey R.; Frisch, Mark; Malhotra, Sanjay V.
Carbohydrate Research, 2011 , vol. 346, # 15 p. 2337 - 2341
参考文献
Goebel; Avery
Journal of Experimental Medicine, 1929 , vol. 50, p. 521,528
反应条件
1: 4-nitro-phenol With 1-n-butyl-3-methylimidazolium chloride; silver(l) oxide T=25°C; Koenigs-Knorr type coupling; 0.25 h; Darknessneat (no solvent); 2: 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide T=25 - 80°C; Koenigs-Knorr type coupling; 0.5 h; Darknessneat (no solvent); optical yield given as percent destereoselective reaction;
参考文献
Kumar, Vineet; Talisman, Ian Jamie; Malhotra, Sanjay V.
European Journal of Organic Chemistry, 2010 , # 18 p. 3377 - 3381
反应条件
1: tetrabutylammomium bromide; sodium hydroxide / dichloromethane / 4 h / 40 °C 2: methanol; sodium methylate / 3 h / 20 °C 3: zinc(II) chloride / 12 h / 20 °C 4: pyridine / 10 h / 20 °C 5: acetic acid / 3 h / 80 °C 6: boron trifluoride diethyl etherate / dichloromethane / 20 h / 20 °C / Inert atmosphere; Molecular sieve 7: methanol; sodium methylate / 3 h / 20 °C View Scheme
参考文献
Wang, Chao; Zhang, Tian-Tai; Du, Guan-Hua; Zhang, Dong-Ming
Journal of Asian Natural Products Research, 2011 , vol. 13, # 9 p. 817 - 825
反应条件
1: 30 percent / Ag2CO3 / acetonitrile / 48 h / 20 °C 2: 61 percent / Pd(OAc02; benzyltriethylammonium chloride; Bu3N / acetonitrile / 2 h / 100 °C 3: 97 percent / NaOMe / methanol / 1 h / 20 °C View Scheme
参考文献
Learmonth, David A.
Synthetic Communications, 2004 , vol. 34, # 9 p. 1565 - 1575
反应条件
1: 42 percent / KOH; triethylbenzylammonium chloride / CHCl3; H2O / Heating 2: 56 percent / 1M NaOMe / methanol View Scheme
参考文献
Dimmock; Erciyas; Raghavan; Kirkpatrick
Pharmazie, 1990 , vol. 45, # 10 p. 755 - 757
反应条件
silver imidazolate; zinc(II) chloride glycosylation;
参考文献
Chenault, H. Keith; Yang, Jie; Taber, Douglass F.
Tetrahedron, 2000 , vol. 56, # 23 p. 3673 - 3677
反应条件
1: o-hydroxynitrobenzene With 1-n-butyl-3-methylimidazolium chloride; silver(l) oxide T=25°C; Koenigs-Knorr type coupling; 0.25 h; Darknessneat (no solvent); 2: 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide T=25 - 80°C; Koenigs-Knorr type coupling; 0.5 h; Darknessneat (no solvent); optical yield given as percent destereoselective reaction;
参考文献
Kumar, Vineet; Talisman, Ian Jamie; Malhotra, Sanjay V.
European Journal of Organic Chemistry, 2010 , # 18 p. 3377 - 3381
反应条件
tetrabutylammomium bromide; sodium hydroxide in dichloromethane; water 8 h; Reflux;
参考文献
Chen, Chao-Yue; Sun, Jian-Guo; Liu, Fei-Yan; Fung, Kwok-Pui; Wu, Ping; Huang, Zhi-Zhen
Tetrahedron, 2012 , vol. 68, # 12 p. 2598 - 2606
反应条件
potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in chloroform; water Koenigs-Knorr reaction; Heating;
参考文献
Pavlov; Sokolov; Zakharov
Russian Journal of General Chemistry, 2001 , vol. 71, # 11 p. 1811 - 1814
