3,4-二氢-2H-吡咯-5-羧酸甲酯合成路线 （共 13 条）
反应条件
1: HCl, 2.) aq. K2CO3
2: tert-butyl hypochlorite / diethyl ether / 0.75 h / 0 °C
3: Et3N / diethyl ether / 18 h / Ambient temperature
View Scheme
参考文献
Kimpe, Norbert G. De; Stevens, Christian V.; Keppens, Marian A.
Journal of Agricultural and Food Chemistry, 1993 , vol. 41, # 9 p. 1458 - 1461
反应条件
1: thionyl chloride / 20 °C / Cooling
2: N-chloro-succinimide; triethylamine / dichloromethane / 3 h / 20 °C
View Scheme
参考文献
Reuter, Cedric; Huy, Peter; Neudoerfl, Joerg-Martin; Kuehne, Ronald; Schmalz, Hans-Guenther
Chemistry - A European Journal, 2011 , vol. 17, # 43 p. 12037 - 12044
反应条件
in benzene
T=80°C; 9 h; Further byproducts given;
参考文献
Haeusler, Johannes
Liebigs Annalen der Chemie, 1981 , # 6 p. 1073 - 1088
