1-Boc-哌嗪合成路线

参考文献

Bristol-Myers Squibb Company
Patent: US2007/249579 A1, 2007 ;
Location in patent: Page/Page column 132 ;

77290-31-41-BOC-4-氰甲基哌嗪

参考文献

AstraZeneca AB
Patent: US2004/48881 A1, 2004 ;
US 20040048881 A1

16629-19-92-噻吩磺酰氯+

57260-71-61-Boc-哌嗪

774575-85-84-(2-噻吩磺酰基)-哌嗪-1-羧酸叔丁酯

参考文献

AMGEN INC.; ASHTON, Kate; BARTBERGER, Michael David; BO, Yunxin; BRYAN, Marian C.; CROGHAN, Michael; FOTSCH, Christopher Harold; HALE, Clarence Henderson; KUNZ, Roxanne Kay; LIU, Longbin; NISHIMURA, Nobuko; NORMAN, Mark H.; PENNINGTON, Lewis Dale; POON, Steve Fong; STEC, Markian Myroslaw; ST. JEAN, David, Joseph, Jr.; TAMAYO, Nuria A.; TEGLEY, Christopher Michael; YANG, Kevin Chao
Patent: WO2012/27261 A1, 2012 ;
Location in patent: Page/Page column 144 ;
WO 2012/027261 A1

1722-12-92-氯嘧啶+

57260-71-61-Boc-哌嗪

780705-64-8

参考文献

Larsen, Matthew A.; Hartwig, John F.
Journal of the American Chemical Society, 2014 , vol. 136, # 11 p. 4287 - 4299

4595-60-22-溴嘧啶+

57260-71-61-Boc-哌嗪

780705-64-8

参考文献

Salituro, Francesco G.; Saunders, Jeffrey O.; Yan, Shunqi
Patent: US2010/331307 A1, 2010 ;
Location in patent: Page/Page column 27 ;
US 20100331307 A1

6452-47-7甲胺基甲酰氯+

57260-71-61-Boc-哌嗪

652154-14-8

参考文献

ASTELLAS PHARMA INC.; ALCON RESEARCH, LTD.
Patent: US2012/46285 A1, 2012 ;
Location in patent: Page/Page column 25 ;
US 20120046285 A1

624-83-9异氰酸甲酯+

57260-71-61-Boc-哌嗪

652154-14-8

参考文献

Ren, Yu; Karki, Shyam B.; Zhao, Matthew M.; Bidodeau, Mark T.
Patent: US2004/23981 A1, 2004 ;
Location in patent: Page/Page column 16 ;
US 20040023981 A1

57260-71-61-Boc-哌嗪

681482-86-0

参考文献

Berlin, Michael; Ting, Pauline C.; Vaccaro, Wayne D.; Aslanian, Robert; McCormick, Kevin D.; Lee, Joe F.; Albanese, Margaret M.; Mutahi, Mwangi W.; Piwinski, John J.; Shih, Neng-Yang; Duguma, Luli; Solomon, Daniel M.; Zhou, Wei; Sher, Rosy; Favreau, Leonard; Bryant, Matthew; Korfmacher, Walter A.; Nardo, Cymbelene; West Jr., Robert E.; Anthes, John C.; Williams, Shirley M.; Wu, Ren-Long; Susan She; Rivelli, Maria A.; Corboz, Michel R.; Hey, John A.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 4 p. 989 - 994

41667-95-25,6-二氯烟酸+

57260-71-61-Boc-哌嗪

683241-92-16-(4-(叔丁氧基羰基)哌嗪-1-基)-5-氯烟酸

参考文献

Bach, Peter; Bostroem, Jonas; Brickmann, Kay; Van Giezen; Groneberg, Robert D.; Harvey, Darren M.; O'Sullivan, Michael; Zetterberg, Fredrik
European Journal of Medicinal Chemistry, 2013 , vol. 65, p. 360 - 375

57260-71-61-Boc-哌嗪

683241-92-16-(4-(叔丁氧基羰基)哌嗪-1-基)-5-氯烟酸

参考文献

Shao, Yuefei; Anilkumar, Gopinadhan N.; Carroll, Carolyn Diianni; Dong, Guizhen; Hall III, James W.; Hobbs, Doug W.; Jiang, Yueheng; Jenh, Chung-Her; Kim, Seong Heon; Kozlowski, Joseph A.; McGuinness, Brian F.; Rosenblum, Stuart B.; Schulman, Inna; Shih, Neng-Yang; Shu, Youheng; Wong, Michael K.C.; Yu, Wensheng; Zawacki, Lisa Guise; Zeng, Qingbei
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 5 p. 1527 - 1531