4’-硝基[1,1’-联苯]-4-甲酸甲酯合成路线 (共 19 条)
反应条件
1: tert.-butylnitrite; toluene-4-sulfonic acid / 1,2-dichloro-ethane / 4 h / 0 °C / |Inert atmosphere 2: tetrakis(triphenylphosphine) palladium(0) / toluene / 12 h / 110 °C / |Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 44 p. 11581 - 11584
Angew. Chem., , vol. 125, # 44 p. 11795 - 11798
参考文献
Journal of the American Chemical Society, , vol. 76, p. 4543,4544
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate; potassium iodide 1.) DMF, 80 deg C; 2.) DME, reflux; 3.) MeOH, THF, reflux; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 35, # 49 p. 9177 - 9180
反应条件
(i) NaNO2, aq. HCl, (ii) /BRN= 1072099/; Multistep reaction;
参考文献
Journal of the Chemical Society, , p. 554 - 562
反应条件
hydrogenchloride Combinatorial reaction / High throughput screening (HTS); Product distribution / selectivity;
参考文献
US2007/43234 A1, ;
Page/Page column 51 ;
反应条件
1: Fe, aq. HCl / methanol 2: aq. KOH / methanol View Scheme
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
反应条件
lithium hydroxide monohydrate; water in tetrahydrofuran; methanol T=20°C; 22 h;
参考文献
Adachi, Yusuke; Nakagawa, Hidehiko; Matsuo, Kazuya; Suzuki, Takayoshi; Miyata, Naoki
Chemical Communications, 2008 , # 41 p. 5149 - 5151
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 15 h;
参考文献
Venkatraj, Muthusamy; Messagie, Jonas; Joossens, Jurgen; Lambeir, Anne-Marie; Haemers, Achiel; Van Der Veken, Pieter; Augustyns, Koen
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 4 p. 1557 - 1568
参考文献
Bly,R.S. et al.
Journal of Organometallic Chemistry, 1976 , vol. 117, p. 35 - 54