N-(2-溴乙基)邻苯二甲酰亚胺合成路线 （共 110 条）
参考文献
Putochin
Chemische Berichte, 1926 , vol. 59, p. 627
Chem. Zentralbl., 1928 , vol. 99, # I p. 318
参考文献
Gabriel
Chemische Berichte, 1888 , vol. 21, p. 571
Chemische Berichte, 1905 , vol. 38, p. 2398
反应条件
1: 25 percent / Sodium borohydride / methanol / 0-5 deg C, 2 h., then room temp., 22 h. 2: 3.9 percent / potassium t-butoxide / 2-methyl-propan-2-ol / 5 h / Heating 3: 48 percent / hydrazine hydrate / ethanol / 50 h / Heating View Scheme
参考文献
Wharton, Clifford J.; Wrigglesworth, Roger
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 809 - 814
反应条件
1: 25 percent / Sodium borohydride / methanol / 0-5 deg C, 2 h., then room temp., 22 h. 2: 3.9 percent / potassium t-butoxide / 2-methyl-propan-2-ol / 5 h / Heating 3: 41 percent / potassium hydroxide / H2O / Ambient temperature View Scheme
参考文献
Wharton, Clifford J.; Wrigglesworth, Roger
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 809 - 814
反应条件
xylene beim Erhitzen des Reaktionsprodukts mit wss.HCl;
参考文献
Archer et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 5783
反应条件
T=100°C; Behandeln des Reaktionsprodukts mit Bromwasserstoffsaeure;
参考文献
Gabriel
Chemische Berichte, 1891 , vol. 24, p. 1117
反应条件
hydrogen bromide; acetic acid T=170°C;
参考文献
Gabriel; Stelzner
Chemische Berichte, 1895 , vol. 28, p. 2933
Full Text Show Details
Gabriel
Chemische Berichte, 1888 , vol. 21, p. 571
Chemische Berichte, 1905 , vol. 38, p. 2398
反应条件
triethylamine in toluene
参考文献
Takeda Chemical Industries, Ltd.
Patent: US4987130 A1, 1991 ;
反应条件
sodium carbonate in water; N,N-dimethyl-formamide 20 h; Heating;
参考文献
Sami; Remers; Bradner
Journal of Medicinal Chemistry, 1989 , vol. 32, # 3 p. 703 - 708
反应条件
1: 54 percent / tetrahydrofuran; cyclohexane; diethyl ether / -40 deg C, 40 min, room temp., 17 h
2: 55 percent / tetrahydrofuran; cyclohexane; diethyl ether / 5 h / -40 - 13 °C
3: 67 percent / hydrazine hydrate / ethanol / 17 h / Ambient temperature
View Scheme
参考文献
Wharton, Clifford J.; Wrigglesworth, Roger
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 809 - 814
