2’-甲基联苯-4-甲酸合成路线 (共 21 条)
反应条件
sodium hydroxide in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 4 p. 437 - 450
反应条件
1: 1.) n-BuLi, 2.) ZnCl2, 3.) (Ph3P)2PdCl2, (i-Bu)2AlH 2: aq. NaOH / tetrahydrofuran / 2 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 4 p. 437 - 450
反应条件
water in methanol T=30 - 50°C; ΔH(excit), ΔS(excit), log A; Rate constantThermodynamic dataKinetics;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 1 p. 35 - 38
反应条件
chromium(VI) oxide; acetic acid
参考文献
Journal of the Chemical Society, , p. 1288,1291
Journal of the Chemical Society, , p. 369,370
反应条件
1: acetic acid; acetic acid anhydride; phosphorus (V)-oxide; nitrogen oxide 3: chromium (VI)-oxide; aqueous acetic acid View Scheme
参考文献
Journal of the Chemical Society, , p. 1288,1291
Journal of the Chemical Society, , p. 369,370
反应条件
1: 18 °C 2: chromium (VI)-oxide; aqueous acetic acid View Scheme
参考文献
Journal of the Chemical Society, , p. 1288,1291
Journal of the Chemical Society, , p. 369,370
反应条件
1: 18 °C 2: chromium (VI)-oxide; aqueous acetic acid View Scheme
参考文献
Journal of the Chemical Society, , p. 1288,1291
Journal of the Chemical Society, , p. 369,370
反应条件
anschliessend mit wss.-methanol. KOH behandeln;
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
反应条件
(i) (diazotization), (ii) /BRN= 1072099/, aq. NaOH, (iii) aq. KOH, MeOH; Multistep reaction;
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
反应条件
1: (i) SOCl2, (ii) aq. NH3 2: aq. NaOBr View Scheme
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845